New Database Available - Released on 23/03/2024.
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335
Unique InChIKey
42
Unique Sequence
199
EC50 Parameter
21
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR1A1 Q9P1Q5 100 homo sapiens MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9TUA7 100 pan troglodytes MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T99M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens G108A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens N109K MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T110A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens I114T MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens V254T MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T277V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens R128H MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens V233M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens P285S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens A106G MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens A106T MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens N109D MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens D111A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens D111S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens S112A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens G152A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens N155S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens S248F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y250F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y251F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y251M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y258F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y258M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y276F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y276L MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T277M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T280A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T280F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T280M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G108A_N109K MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens A154T_N155S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G108A_G152A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G108A_I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens D111A_T280A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens D111S_T280A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G152A_I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.029 homo sapiens G108A_G152A_I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 98.706 homo sapiens G108A_N109K_A154T_N155S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
Experiments Pair Aggregation
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Species
Gene Name
UniProt ID
Mutation
Sequence
Molecule Name
CID
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SMILES
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Responsive
Parameter
Value
Unit
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Nbr. measurements
Type
Cell_line
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Gprotein
Co-transfection
Assay System
Tag
Reference
DOI
Reference Position
homo sapiens OR1A1 Q9P1Q5 T280F MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 T280M MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 G108A_N109K MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 G108A_G152A MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 G108A_I205V MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 D111A_T280A MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 D111S_T280A MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 G152A_I205V MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 1 ec50 489.17 uM 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
homo sapiens OR1A1 Q9P1Q5 G108A_G152A_I205V MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Table_S8
pan troglodytes OR1A1 Q9TUA7 MRENNQSSTLEFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 1 ec50 >100 uM 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_2D
pan troglodytes OR1A1 Q9TUA7 MRENNQSSTLEFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 1 ec50 >100 uM 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_2D
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (S)-2-Phenylbutanoic acid 785329 OFJWFSNDPCAWDK-VIFPVBQESA-N CC[C@@H](C1=CC=CC=C1)C(=O)O mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (+)-Camphor 159055 DSSYKIVIOFKYAU-XCBNKYQSSA-N C[C@@]12CC[C@@H](C1(C)C)CC2=O mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 1 ec50 9.226 uM 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (+)-Dihydrocarvone 24473 AZOCECCLWFDTAP-UHFFFAOYSA-N CC1CCC(CC1=O)C(=C)C sum of isomers 1 ec50 10.186 uM 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (+)-Fenchone 1201521 LHXDLQBQYFFVNW-XCBNKYQSSA-N C[C@]12CC[C@H](C1)C(C2=O)(C)C mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (R)-(-)-2-Phenylbutyric acid 785330 OFJWFSNDPCAWDK-SECBINFHSA-N CC[C@H](C1=CC=CC=C1)C(=O)O mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (-)-Camphor 444294 DSSYKIVIOFKYAU-OIBJUYFYSA-N C[C@]12CC[C@H](C1(C)C)CC2=O mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 1 ec50 1.718 uM 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (-)-Fenchone 82229 LHXDLQBQYFFVNW-OIBJUYFYSA-N C[C@@]12CC[C@@H](C1)C(C2=O)(C)C mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (-)-beta-Citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 91.411 uM 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-Decanol 8174 MWKFXSUHUHTGQN-UHFFFAOYSA-N CCCCCCCCCCO mono 1 ec50 827.942 uM 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-Heptanol 8129 BBMCTIGTTCKYKF-UHFFFAOYSA-N CCCCCCCO mono 1 ec50 970.51 uM 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-Hexanol 8103 ZSIAUFGUXNUGDI-UHFFFAOYSA-N CCCCCCO mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-Nonanol 8914 ZWRUINPWMLAQRD-UHFFFAOYSA-N CCCCCCCCCO mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-Octanol 957 KBPLFHHGFOOTCA-UHFFFAOYSA-N CCCCCCCCO mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-Pentanol 6276 AMQJEAYHLZJPGS-UHFFFAOYSA-N CCCCCO mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Coumaranone 68382 ACZGCWSMSTYWDQ-UHFFFAOYSA-N C1C2=CC=CC=C2OC1=O mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Heptanone 8051 CATSNJVOTSVZJV-UHFFFAOYSA-N CCCCCC(=O)C mono 1 ec50 39.902 uM 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Hexanone 11583 QQZOPKMRPOGIEB-UHFFFAOYSA-N CCCCC(=O)C mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
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