127
Unique InChIKey
6
Unique Sequence
1
EC50 Parameter
13
Unique DOI
BLAST
OR2A1 | Q8NGT9 | 100 | homo sapiens | MGENQTMVTEFLLLG ... | MGENQTMVTEFLLLG ... | ||
OR2A1 | A0A126GVC1 | 100 | homo sapiens | MGENQTMVTEFLLLG ... | MGENQTMVTEFLLLG ... | ||
OR2A1 | Q8NGT9 | 100 | homo sapiens | M1-_G2-_E3-_N4-_Q5-_T6- | MVTEFLLLGFLLGPR ... | MGENQTMVTEFLLLG ... | |
OR2A1 | Q8NGT9 | 99.677 | homo sapiens | S168C | MGENQTMVTEFLLLG ... | MGENQTMVTEFLLLG ... | |
OR2A1 | Q8NGT9 | 99.032 | homo sapiens | T73A_R74C_S168C | MGENQTMVTEFLLLG ... | MGENQTMVTEFLLLG ... | |
OR2A1 | Q8NGT9 | 98.355 | homo sapiens | M1-_G2-_E3-_N4-_Q5-_T6-_F279S_ ... | MVTEFLLLGFLLGPR ... | MGENQTMVTEFLLLG ... |
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homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | α-pinene | 6654 | 80-56-8 | GRWFGVWFFZKLTI-UHFFFAOYSA-N | CC1=CCC2CC1C2(C)C | sum of isomers | 1 | norm_other | 800 | uM | 3 | GFP | Yeast | liquid | in vitro | millipore guava easycyte ht flow cytometer | Rapid deorphanization of human ... | https://doi.org/10.1021/acs.bi ... | Figure_2B | ||||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | farnesol | 445070 | 4602-84-0 | CRDAMVZIKSXKFV-YFVJMOTDSA-N | CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C | mono | 1 | norm_other | 200 | uM | 3 | GFP | Yeast | liquid | in vitro | millipore guava easycyte ht flow cytometer | Rapid deorphanization of human ... | https://doi.org/10.1021/acs.bi ... | Figure_2B | ||||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | farnesol | 445070 | 4602-84-0 | CRDAMVZIKSXKFV-YFVJMOTDSA-N | CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C | mono | 1 | norm_other | 400 | uM | 3 | GFP | Yeast | liquid | in vitro | millipore guava easycyte ht flow cytometer | Rapid deorphanization of human ... | https://doi.org/10.1021/acs.bi ... | Figure_2B | ||||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | farnesol | 445070 | 4602-84-0 | CRDAMVZIKSXKFV-YFVJMOTDSA-N | CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C | mono | 1 | norm_other | 600 | uM | 3 | GFP | Yeast | liquid | in vitro | millipore guava easycyte ht flow cytometer | Rapid deorphanization of human ... | https://doi.org/10.1021/acs.bi ... | Figure_2B | ||||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | farnesol | 445070 | 4602-84-0 | CRDAMVZIKSXKFV-YFVJMOTDSA-N | CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C | mono | 1 | norm_other | 800 | uM | 3 | GFP | Yeast | liquid | in vitro | millipore guava easycyte ht flow cytometer | Rapid deorphanization of human ... | https://doi.org/10.1021/acs.bi ... | Figure_2B | ||||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | farnesol | 445070 | 4602-84-0 | CRDAMVZIKSXKFV-YFVJMOTDSA-N | CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C | mono | 1 | norm_other | 1000 | uM | 3 | GFP | Yeast | liquid | in vitro | millipore guava easycyte ht flow cytometer | Rapid deorphanization of human ... | https://doi.org/10.1021/acs.bi ... | Figure_2B | ||||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | farnesol | 445070 | 4602-84-0 | CRDAMVZIKSXKFV-YFVJMOTDSA-N | CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C | mono | 0 | ec50 | n.d | n.d | 1000 | uM | 3 | GFP | Yeast | liquid | in vitro | millipore guava easycyte ht flow cytometer | Rapid deorphanization of human ... | https://doi.org/10.1021/acs.bi ... | Figure_3C | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 3-Mercaptohexyl acetate | 518810 | JUCARGIKESIVLB-UHFFFAOYSA-N | CCCC(CCOC(=O)C)S | sum of isomers | 0 | norm_rec | 100 | uM | 2 | Luc | HEK | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | il-6-halotag | The key food odorant receptive ... | https://doi.org/10.1016/j.food ... | Figure_S3 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | Furaneol | 19309 | INAXVXBDKKUCGI-UHFFFAOYSA-N | CC1C(=O)C(=C(O1)C)O | sum of isomers | 0 | norm_rec | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s | glosensor (promega) | il-6-halotag | Key food furanones furaneol an ... | https://doi.org/10.1021/acs.ja ... | Figure_1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | Sotolone | 62835 | UNYNVICDCJHOPO-UHFFFAOYSA-N | CC1C(=C(C(=O)O1)O)C | sum of isomers | 0 | norm_rec | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s | glosensor (promega) | il-6-halotag | Key food furanones furaneol an ... | https://doi.org/10.1021/acs.ja ... | Figure_1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | homofuraneol | 33931 | GWCRPYGYVRXVLI-UHFFFAOYSA-N | CCC1C(=O)C(=C(O1)C)O | sum of isomers | 0 | norm_rec | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s | glosensor (promega) | il-6-halotag | Key food furanones furaneol an ... | https://doi.org/10.1021/acs.ja ... | Figure_1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | Abhexone | 61199 | IUFQZPBIRYFPFD-UHFFFAOYSA-N | CCC1C(=C(C(=O)O1)O)C | sum of isomers | 0 | norm_rec | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s | glosensor (promega) | il-6-halotag | Key food furanones furaneol an ... | https://doi.org/10.1021/acs.ja ... | Figure_1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | Allyl Phenyl acetate | 15717 | 1746-13-0 | ZCDYAMJXVAUTIM-UHFFFAOYSA-N | C=CCOC(=O)CC1=CC=CC=C1 | mono | 0 | norm_rec | 100 | uM | 2 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | il-6-halotag | IL-6–HaloTag® enables live- ... | https://doi.org/10.14440/jbm.2 ... | Figure_5 | |||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 2,3,5-Trimethylpyrazine | 26808 | 14667-55-1 | IAEGWXHKWJGQAZ-UHFFFAOYSA-N | CC1=CN=C(C(=N1)C)C | mono | 0 | norm_rec | 100 | uM | 3 | Luc | HEK | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | il-6-halotag | An evolutionary conserved olfa ... | https://doi.org/10.1096/fj.202 ... | Figure_1A | |||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 2,4,5-trimethyl-4,5-dihydrothiazole | 263626 | 4145-93-1 | CIEKNJJOENYFQL-UHFFFAOYSA-N | CC1C(SC(=N1)C)C | sum of isomers | 0 | norm_rec | 100 | uM | 3 | Luc | HEK | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | il-6-halotag | An evolutionary conserved olfa ... | https://doi.org/10.1096/fj.202 ... | Figure_1B | |||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 3-mercapto-2-methylpentan-1-ol | 6430888 | HABNNYNSJFKZFE-UHFFFAOYSA-N | CCC(C(C)CO)S | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_S1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 2-methyl-3-sulfanylpropan-1-ol | 529079 | FCIVYWQHILCTLI-UHFFFAOYSA-N | CC(CO)CS | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_3E | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 2-Methyl-3-sulfanylheptan-1-ol | 21997288 | OCZSUTGSYBERRF-UHFFFAOYSA-N | CCCCC(C(C)CO)S | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_3E | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 3-Mercapto-2-methyloctan-1-ol | CCCCCC(C(C)CO)S | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_3E | ||||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | (+/-)-Muscone | 10947 | 541-91-3 | ALHUZKCOMYUFRB-UHFFFAOYSA-N | CC1CCCCCCCCCCCCC(=O)C1 | sum of isomers | 0 | norm_other | 0 | 100 | uM | 3 | Luc | HEK | liquid | in vitro | rtp1s-pme18s | dual-glo luciferase assay system | flag | Ligand specificity and evoluti ... | https://doi.org/10.1523/JNEURO ... | Figure_4A | |||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | Musk xylol | 62329 | XMWRWTSZNLOZFN-UHFFFAOYSA-N | CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... | mono | 0 | norm_other | 0 | 100 | uM | 3 | Luc | HEK | liquid | in vitro | rtp1s-pme18s | dual-glo luciferase assay system | flag | Ligand specificity and evoluti ... | https://doi.org/10.1523/JNEURO ... | Figure_4A | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | musk ketone | 6669 | WXCMHFPAUCOJIG-UHFFFAOYSA-N | CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... | mono | 0 | norm_other | 0 | 100 | uM | 3 | Luc | HEK | liquid | in vitro | rtp1s-pme18s | dual-glo luciferase assay system | flag | Ligand specificity and evoluti ... | https://doi.org/10.1523/JNEURO ... | Figure_4A | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | (Z)-4-undecenal | 5362881 | QGNDNDFXCNBMKI-FPLPWBNLSA-N | CCCCCC/C=C\CCC=O | mono | 0 | norm_pair | 100 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor™-22f | il-6-halotag | The human odorant receptor OR1 ... | https://doi.org/10.1101/2020.1 ... | Fig_3 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 3-Methyl-2,4-nonanedione | 529481 | BGVBGAIWXAXBLP-UHFFFAOYSA-N | CCCCCC(=O)C(C)C(=O)C | sum of isomers | 0 | norm_rec | 30 | uM | 3 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor-22f | rho | The Broadly Tuned Odorant Rece ... | https://doi.org/10.1093/chemse ... | Fig_6 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | 3-Methyl-2,4-nonanedione | 529481 | BGVBGAIWXAXBLP-UHFFFAOYSA-N | CCCCCC(=O)C(C)C(=O)C | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor-22f | rho | The Broadly Tuned Odorant Rece ... | https://doi.org/10.1093/chemse ... | Fig_S5 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | (e)-8-Cyclohexadecen-1-one | 5362739 | ZGEHHVDYDNXYMW-UPHRSURJSA-N | C1CCC/C=C\CCCCCCC(=O)CCC1 | mono | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | (5E)-3-methylcyclopentadec-5-en-1-one | 9834606 | NKMKFQCVDZVEJR-CSKARUKUSA-N | CC1C/C=C/CCCCCCCCCC(=O)C1 | mono | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | Ambrettolide | 5365703 | NVIPUOMWGQAOIT-RQOWECAXSA-N | C1CCCCOC(=O)CCCCC/C=C\CCC1 | mono | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | Galaxolide | 91497 | ONKNPOPIGWHAQC-UHFFFAOYSA-N | CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C | sum of isomers | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR2A1 | Q8NGT9 | MGENQTMVTEFLLLG ... | L-Carvone | 439570 | 6485-40-1 | ULDHMXUKGWMISQ-SECBINFHSA-N | CC1=CC[C@H](CC1=O)C(=C)C | mono | 0 | norm_other | 1.248 | Fold | 300 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s cre luc2ppgl4.29 prl-cmv | dual-glo luciferase | rho | Ieki, Takashi, Yuki Yamanaka, ... | https://doi.org/10.1371/journa ... | Figure_1 |