New Database Available - Released on 23/03/2024.
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137
Unique InChIKey
6
Unique Sequence
92
EC50 Parameter
17
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR2J2 O76002 100 homo sapiens MMIKKNASSEDFFIL ... MMIKKNASSEDFFIL ...
OR2J2 O76002 99.679 homo sapiens A218T MMIKKNASSEDFFIL ... MMIKKNASSEDFFIL ...
OR2J2 O76002 99.038 homo sapiens H74Y_A111T_A146V MMIKKNASSEDFFIL ... MMIKKNASSEDFFIL ...
OR2J2 O76002 98.718 homo sapiens H74Y_A111T_A146V_A218T MMIKKNASSEDFFIL ... MMIKKNASSEDFFIL ...
OR2J2 O76002 99.038 homo sapiens H74Y_A111T_A218T MMIKKNASSEDFFIL ... MMIKKNASSEDFFIL ...
OR2J2 O76002 99.038 homo sapiens H74Y_A146V_A218T MMIKKNASSEDFFIL ... MMIKKNASSEDFFIL ...
Experiments Pair Aggregation
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homo sapiens
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Reference Position
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... Phenyl acetate 31229 IPBVNPXQWQGGJP-UHFFFAOYSA-N CC(=O)OC1=CC=CC=C1 mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... Prenyl acetate 14489 XXIKYCPRDXIMQM-UHFFFAOYSA-N CC(=CCOC(=O)C)C mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... Propionic acid 1032 XBDQKXXYIPTUBI-UHFFFAOYSA-N CCC(=O)O mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... Vanillic acid 8468 WKOLLVMJNQIZCI-UHFFFAOYSA-N COC1=C(C=CC(=C1)C(=O)O)O mono 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... gamma-Caprolactone 12756 JBFHTYHTHYHCDJ-UHFFFAOYSA-N CCC1CCC(=O)O1 sum of isomers 0 ec50 n.d n.d 3000 uM 3 Luc H3A liquid in vitro olf rtp1s cre-luciferase prl-sv40 dualglo rho Saito, H.; Chi, Q.; Zhuang, H. ... https://dx.doi.org/10.1126%2Fs ... Table_S3
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 norm_other 0.255 30 uM 1 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1A
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 30 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_6
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_S5
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... (e)-8-Cyclohexadecen-1-one 5362739 ZGEHHVDYDNXYMW-UPHRSURJSA-N C1CCC/C=C\CCCCCCC(=O)CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... (5E)-3-methylcyclopentadec-5-en-1-one 9834606 NKMKFQCVDZVEJR-CSKARUKUSA-N CC1C/C=C/CCCCCCCCCC(=O)C1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... Ambrettolide 5365703 NVIPUOMWGQAOIT-RQOWECAXSA-N C1CCCCOC(=O)CCCCC/C=C\CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... Galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 0.416 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 0.683 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 2.016 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 1 norm_other 84.24 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 1 norm_other 55.976 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.027 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 1 ec50 64 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 1 ec50 34 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 1 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 40.417 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 ec50 33.2 99.59 33.2 33.2 33.2 99.59 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S3
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 2.739 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 ec50 >300 900 300 300 300 900 uM 300 900 300 300 300 900 uM 3 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S4
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.702 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 4.085 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR2J2 O76002 MMIKKNASSEDFFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 ec50 n.d n.d 3000 uM 3 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S6
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