New Database Available - Released on 23/03/2024.
85
Unique InChIKey
3
Unique Sequence
0
EC50 Parameter
14
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR51B4 Q9Y5P0 100 homo sapiens MWYNNSAGPFLLTGF ... MWYNNSAGPFLLTGF ...
OR51B4 Q9Y5P0 99.677 homo sapiens M147T MWYNNSAGPFLLTGF ... MWYNNSAGPFLLTGF ...
OR51B4 Q9Y5P0 99.355 homo sapiens V36I_M147T MWYNNSAGPFLLTGF ... MWYNNSAGPFLLTGF ...
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homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... 5-Methyl-2-(1-methylbutyl)-5-propyl-1,3-dioxane 166523 LODLFUCEWWWXPR-UHFFFAOYSA-N CCCC(C)C1OCC(CO1)(C)CCC sum of isomers 0 norm_mol 10 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... 5-Methyl-2-(1-methylbutyl)-5-propyl-1,3-dioxane 166523 LODLFUCEWWWXPR-UHFFFAOYSA-N CCCC(C)C1OCC(CO1)(C)CCC sum of isomers 0 norm_mol 50 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... 5-Methyl-2-(1-methylbutyl)-5-propyl-1,3-dioxane 166523 LODLFUCEWWWXPR-UHFFFAOYSA-N CCCC(C)C1OCC(CO1)(C)CCC sum of isomers 1 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... 5-Methyl-2-(1-methylbutyl)-5-propyl-1,3-dioxane 166523 LODLFUCEWWWXPR-UHFFFAOYSA-N CCCC(C)C1OCC(CO1)(C)CCC sum of isomers 1 norm_mol 300 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... 5-Methyl-2-(1-methylbutyl)-5-propyl-1,3-dioxane 166523 LODLFUCEWWWXPR-UHFFFAOYSA-N CCCC(C)C1OCC(CO1)(C)CCC sum of isomers 1 norm_mol 500 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Lyral 91604 ORMHZBNNECIKOH-UHFFFAOYSA-N CC(C)(CCCC1=CCC(CC1)C=O)O sum of isomers 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Citral 638011 WTEVQBCEXWBHNA-JXMROGBWSA-N CC(=CCC/C(=C/C=O)/C)C mono 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Citronellal 7794 NEHNMFOYXAPHSD-UHFFFAOYSA-N CC(CCC=C(C)C)CC=O sum of isomers 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Terpineol 17100 WUOACPNHFRMFPN-UHFFFAOYSA-N CC1=CCC(CC1)C(C)(C)O sum of isomers 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Limonene 22311 XMGQYMWWDOXHJM-UHFFFAOYSA-N CC1=CCC(CC1)C(=C)C sum of isomers 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Dimetol 83268 HGDVHRITTGWMJK-UHFFFAOYSA-N CC(C)CCCC(C)(C)O mono 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Rose oxide 27866 CZCBTSFUTPZVKJ-UHFFFAOYSA-N CC1CCOC(C1)C=C(C)C sum of isomers 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Butanone 6569 ZWEHNKRNPOVVGH-UHFFFAOYSA-N CCC(=O)C mono 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Nerol 643820 GLZPCOQZEFWAFX-YFHOEESVSA-N CC(=CCC/C(=C\CO)/C)C mono 0 norm_mol 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Weber, Lea, et al. "Activation ... https://doi.org/10.1371/journa ... Figure_3
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... (e)-8-Cyclohexadecen-1-one 5362739 ZGEHHVDYDNXYMW-UPHRSURJSA-N C1CCC/C=C\CCCCCCC(=O)CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... (5E)-3-methylcyclopentadec-5-en-1-one 9834606 NKMKFQCVDZVEJR-CSKARUKUSA-N CC1C/C=C/CCCCCCCCCC(=O)C1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Ambrettolide 5365703 NVIPUOMWGQAOIT-RQOWECAXSA-N C1CCCCOC(=O)CCCCC/C=C\CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.17 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 0.958 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 0.909 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 3.631 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 3.182 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 0.892 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... Butter aroma recombinate (diacetyl, butanoic acid, delta-decalactone) QSJXEFYPDANLFS-UHFFFAOYSA-N FE ... CC(=O)C(=O)C CCCC(=O)O CCCCCC1CCCC(=O)O1 mixture 0 norm_pair 4 41 29 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.136 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.232 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51B4 Q9Y5P0 MWYNNSAGPFLLTGF ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.847 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2