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244
Unique InChIKey
9
Unique Sequence
216
EC50 Parameter
17
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR5K1 A0A3Q7SVK8 100 vulpes vulpes MAEENHTLKSEFILT ... MAEENHTLKSEFILT ...
OR5K1 A0A8P0TCS6 100 canis lupus familiaris MAEENHTLKSEFILT ... MAEENHTLKSEFILT ...
OR5K1 Q8NHB7 100 homo sapiens MAEENHTMKNEFILT ... MAEENHTMKNEFILT ...
OR5K1 Q8NHB7 99.675 homo sapiens F62L MAEENHTMKNEFILT ... MAEENHTMKNEFILT ...
OR5K1 A0A6P6H1F7 100 puma concolor MAEENHTMKSEFILT ... MAEENHTMKSEFILT ...
OR5K1 A0A6P3DZI2 100 ovis aries MAKENHTIKNEFILT ... MAKENHTIKNEFILT ...
OR5K1 E1BM68 100 bos taurus MAKENHTIKSEFILT ... MAKENHTIKSEFILT ...
OR5K1 A0A2R8ZIW4 100 pan paniscus MTEENHTMKNEFILM ... MTEENHTMKNEFILM ...
OR5K1 A0A6D2VUS1 100 pan troglodytes MTEENHTMKNEFILM ... MTEENHTMKNEFILM ...
Experiments Pair Aggregation
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Species
bos taurus
ovis aries
canis lupus familiaris
vulpes vulpes
puma concolor
homo sapiens
pan paniscus
pan troglodytes
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Species
Gene Name
UniProt ID
Mutation
Sequence
Molecule Name
CID
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Value
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Nbr. measurements
Type
Cell_line
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Gprotein
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Assay System
Tag
Reference
DOI
Reference Position
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... 2-Ethyl-3,5(6)-dimethylpyrazine JZBCTZLGKSYRSF-UHFFFAOYSA-N WH ... CCC1=NC=C(N=C1C)C CCC1=NC(=CN=C1C)C mixture 1 ec50 21.18 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... 2-Acetyl-3,5(6)-dimethylpyrazine UCGOSAWBWFUKDT-UHFFFAOYSA-N JF ... CC1=CN=C(C(=N1)C)C(=O)C CC1=CN=C(C(=N1)C ... mixture 1 ec50 197.82 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... 2-Ethyl-5(6)-methylpyrazine RAFHQTNQEZECFL-UHFFFAOYSA-N OX ... CCC1=NC(=CN=C1)C CCC1=NC=C(N=C1)C mixture 1 ec50 486.28 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... methyl (2R)-2/(2S)-2/3-methylbutanoate, sum of isomers OQAGVSWESNCJJT-UHFFFAOYSA-N OC ... CC(C)CC(=O)OC CCC(C)C(=O)OC mixture 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1C
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 1 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 1 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 4.243 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 ec50 n.d n.d 300 900 300 300 300 900 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S3
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.019 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.637 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.239 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... 2,4,5-trimethyl-2,5-dihydro-1,3-thiazole 181287 60633-24-1 AIVVNNYXOSPRCW-UHFFFAOYSA-N CC1C(=NC(S1)C)C sum of isomers 1 ec50 -8.513 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 1 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4B
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4A
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 1 ec50 11 uM 500 uM 3 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... TableS2
homo sapiens OR5K1 Q8NHB7 MAEENHTMKNEFILT ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 ec50 n.d n.d 500 uM 3 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... TableS2
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2-Isobutyl-3-methoxypyrazine 32594 UXFSPRAGHGMRSQ-UHFFFAOYSA-N CC(C)CC1=NC=CN=C1OC mono 1 ec50 378.36 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... (2R/2S)-4-methoxy-2,5-dimethylfuran-3(2H)-one 61325 SIMKGHMLPVDSJE-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)OC sum of isomers 0 ec50 n.d n.d 1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2-Acetyl-3-ethylpyrazine 61918 PPJSYGVFDJEMRP-UHFFFAOYSA-N CCC1=NC=CN=C1C(=O)C mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2-Acetyl-3-methylpyrazine 32093 QUNOTZOHYZZWKQ-UHFFFAOYSA-N CC1=NC=CN=C1C(=O)C mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2-Ethyl-3-methylpyrazine 27457 LNIMMWYNSBZESE-UHFFFAOYSA-N CCC1=NC=CN=C1C mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2,6-Dimethylpyrazine 7938 HJFZAYHYIWGLNL-UHFFFAOYSA-N CC1=CN=CC(=N1)C mono 1 ec50 554.38 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 5H-5-Methyl-6,7-dihydrocyclopenta-[b]pyrazine 32065 YZEFQPIMXZVPKP-UHFFFAOYSA-N CC1CCC2=NC=CN=C12 sum of isomers 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2-Vinylpyrazine 77840 KANZWHBYRHQMKZ-UHFFFAOYSA-N C=CC1=NC=CN=C1 mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2,3-Dimethylpyrazine 22201 OXQOBQJCDNLAPO-UHFFFAOYSA-N CC1=NC=CN=C1C mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2,5-Dimethylpyrazine 31252 LCZUOKDVTBMCMX-UHFFFAOYSA-N CC1=CN=C(C=N1)C mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2-Methoxypyrazine 18467 WKSXRWSOSLGSTN-UHFFFAOYSA-N COC1=NC=CN=C1 mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
pan paniscus OR5K1 A0A2R8ZIW4 MTEENHTMKNEFILM ... 2-Acetylpyrazine 30914 DBZAKQWXICEWNW-UHFFFAOYSA-N CC(=O)C1=NC=CN=C1 mono 1 ec50 >1500 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Table_S6
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