New Database Available - Released on 23/03/2024.
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93
Unique InChIKey
16
Unique Sequence
21
EC50 Parameter
17
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR7D4_OR7D4P Q8NG98 100 homo sapiens MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens A279D MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens C139R MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens C139Y MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens D52G MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens H131Q MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L162P MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L17F MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L292M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens M136I MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens P79L MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens R88W MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.359 homo sapiens R88W_T133M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens S75C MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens S84N MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens T133M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
Experiments Pair Aggregation
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homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -5.666 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -5.478 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -4.88 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4B
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4A
homo sapiens OR7D4_OR7D4P Q8NG98 L17F MEAENLTELSKFLLL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -5.314 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -4.988 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... (-)-menthol 16666 NOOLISFMXDJSKH-KXUCPTDWSA-N C[C@@H]1CC[C@H]([C@@H](C1)O)C(C)C mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... (+)-menthol 165675 NOOLISFMXDJSKH-AEJSXWLSSA-N C[C@H]1CC[C@@H]([C@H](C1)O)C(C)C mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 1-butanol 263 LRHPLDYGYMQRHN-UHFFFAOYSA-N CCCCO mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 2-butanone 6569 ZWEHNKRNPOVVGH-UHFFFAOYSA-N CCC(=O)C mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 2-decenal 19801 MMFCJPPRCYDLLZ-UHFFFAOYSA-N CCCCCCCC=CC=O sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 2-ethylfenchol 106997 KIPCKEJKGCXRGA-UHFFFAOYSA-N CCC1(C(C2CCC1(C2)C)(C)C)O sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 2-methoxy-4-methylphenol 7144 PETRWTHZSKVLRE-UHFFFAOYSA-N CC1=CC(=C(C=C1)O)OC mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... 4-methylvaleric acid 12587 FGKJLKRYENPLQH-UHFFFAOYSA-N CC(C)CCC(=O)O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... androstadienone 92979 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... bourgeonal 64832 FZJUFJKVIYFBSY-UHFFFAOYSA-N CC(C)(C)C1=CC=C(C=C1)CCC=O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... butyl acetate 31272 DKPFZGUDAPQIHT-UHFFFAOYSA-N CCCCOC(=O)C mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... butyric acid 264 FERIUCNNQQJTOY-UHFFFAOYSA-N CCCC(=O)O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
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