New Database Available - Released on 23/03/2024.
90
Unique InChIKey
16
Unique Sequence
21
EC50 Parameter
14
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens D52G MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens R88W MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.359 homo sapiens R88W_T133M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens H131Q MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens C139Y MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens C139R MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L162P MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens A279D MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L292M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 100 homo sapiens MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens M136I MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens T133M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens S84N MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens P79L MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens S75C MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L17F MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
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homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... phenyl acetaldehyde 998 DTUQWGWMVIHBKE-UHFFFAOYSA-N C1=CC=C(C=C1)CC=O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... pyrazine 9261 KYQCOXFCLRTKLS-UHFFFAOYSA-N C1=CN=CC=N1 mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... r-carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... r-limonene 91691547 JRFITZGBELIFQM-UHFFFAOYSA-N CC(=C)C1CCC2(OC(C1)OO2)C sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... terpineol 17100 WUOACPNHFRMFPN-UHFFFAOYSA-N CC1=CCC(CC1)C(C)(C)O sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... terpinyl acetate 111037 IGODOXYLBBXFDW-UHFFFAOYSA-N CC1=CCC(CC1)C(C)(C)OC(=O)C sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... undecanal 8186 KMPQYAYAQWNLME-UHFFFAOYSA-N CCCCCCCCCCC=O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... vanillin 1183 MWOOGOJBHIARFG-UHFFFAOYSA-N COC1=C(C=CC(=C1)C=O)O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 12 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... Androstadienone 92979 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 1 ec50 2.9 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 30 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_6
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_S5
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... (e)-8-Cyclohexadecen-1-one 5362739 ZGEHHVDYDNXYMW-UPHRSURJSA-N C1CCC/C=C\CCCCCCC(=O)CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... (5E)-3-methylcyclopentadec-5-en-1-one 9834606 NKMKFQCVDZVEJR-CSKARUKUSA-N CC1C/C=C/CCCCCCCCCC(=O)C1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... Ambrettolide 5365703 NVIPUOMWGQAOIT-RQOWECAXSA-N C1CCCCOC(=O)CCCCC/C=C\CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... Galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 10 uM 23 Luc HEK liquid in vitro hrtp1s/hrtp2 Human olfactory receptors deor ... https://doi.org/10.1093/chemse ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 0.866 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 1.035 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.204 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 2.537 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 1.723 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.058 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.862 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.556 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.397 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR7D4_OR7D4P Q8NG98 MEAENLTELSKFLLL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.237 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2