New Database Available - Released on 23/03/2024.
90
Unique InChIKey
16
Unique Sequence
21
EC50 Parameter
14
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR7D4_OR7D4P Q8NG98 100 homo sapiens MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L17F MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens P79L MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens R88W MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens T133M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens S84N MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens D52G MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens S75C MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens H131Q MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens M136I MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens C139R MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens C139Y MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L162P MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens A279D MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.679 homo sapiens L292M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
OR7D4_OR7D4P Q8NG98 99.359 homo sapiens R88W_T133M MEAENLTELSKFLLL ... MEAENLTELSKFLLL ...
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homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... r-carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... r-limonene 91691547 JRFITZGBELIFQM-UHFFFAOYSA-N CC(=C)C1CCC2(OC(C1)OO2)C sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... terpineol 17100 WUOACPNHFRMFPN-UHFFFAOYSA-N CC1=CCC(CC1)C(C)(C)O sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... terpinyl acetate 111037 IGODOXYLBBXFDW-UHFFFAOYSA-N CC1=CCC(CC1)C(C)(C)OC(=O)C sum of isomers 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... undecanal 8186 KMPQYAYAQWNLME-UHFFFAOYSA-N CCCCCCCCCCC=O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... vanillin 1183 MWOOGOJBHIARFG-UHFFFAOYSA-N COC1=C(C=CC(=C1)C=O)O mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 ec50 n.d n.d 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... Androstadienone 92979 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 0 ec50 n.d n.d 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 R88W_T133M MEAENLTELSKFLLL ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR7D4_OR7D4P Q8NG98 P79L MEAENLTELSKFLLL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -2.229 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR7D4_OR7D4P Q8NG98 P79L MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 ec50 n.d n.d 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2C
homo sapiens OR7D4_OR7D4P Q8NG98 P79L MEAENLTELSKFLLL ... Androstadienone 92979 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 0 ec50 n.d n.d 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2C
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 >30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... Androstadienone 92979 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 1 ec50 10 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 R88W MEAENLTELSKFLLL ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR7D4_OR7D4P Q8NG98 T133M MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 17 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 T133M MEAENLTELSKFLLL ... Androstadienone 92979 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 1 ec50 8.9 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2B
homo sapiens OR7D4_OR7D4P Q8NG98 S84N MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 4.2 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2C
homo sapiens OR7D4_OR7D4P Q8NG98 S84N MEAENLTELSKFLLL ... Androstadienone 92979 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 1 ec50 0.52 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2C
homo sapiens OR7D4_OR7D4P Q8NG98 D52G MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 norm_other 3 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2D
homo sapiens OR7D4_OR7D4P Q8NG98 D52G MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 norm_other 30 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2D
homo sapiens OR7D4_OR7D4P Q8NG98 S75C MEAENLTELSKFLLL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 norm_other 3 uM 4 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_2D