New Database Available - Released on 23/03/2024.
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80
Unique InChIKey
3
Unique Sequence
5
EC50 Parameter
14
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR8B2 Q96RD0 100 homo sapiens MLARNNSLVTEFILA ... MLARNNSLVTEFILA ...
OR8B2 Q96RD0 99.681 homo sapiens L164F MLARNNSLVTEFILA ... MLARNNSLVTEFILA ...
OR8B2 Q96RD0 99.681 homo sapiens S273F MLARNNSLVTEFILA ... MLARNNSLVTEFILA ...
Experiments Pair Aggregation
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homo sapiens
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SMILES
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Value
Unit
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Nbr. measurements
Type
Cell_line
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Gprotein
Co-transfection
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Tag
Reference
DOI
Reference Position
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 3-Mercapto-2-methyloctan-1-ol CCCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Acetophenone 7410 KWOLFJPFCHCOCG-UHFFFAOYSA-N CC(=O)C1=CC=CC=C1 mono 0 ec50 n.d n.d 1000 uM 3 Luc H3A liquid in vitro olf rtp1s rtp2 reep1 dualglo (promega) Large-Scale G Protein-Coupled ... https://doi.org/10.1021/acscen ... Table_S5
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... (-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 ec50 n.d n.d 1000 uM 3 Luc H3A liquid in vitro olf rtp1s rtp2 reep1 dualglo (promega) Large-Scale G Protein-Coupled ... https://doi.org/10.1021/acscen ... Table_S5
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... coumarin 323 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N C1=CC=C2C(=C1)C=CC(=O)O2 mono 0 ec50 n.d n.d 1000 uM 3 Luc H3A liquid in vitro olf rtp1s rtp2 reep1 dualglo (promega) Large-Scale G Protein-Coupled ... https://doi.org/10.1021/acscen ... Table_S5
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 4-chromanone 68110 MSTDXOZUKAQDRL-UHFFFAOYSA-N C1COC2=CC=CC=C2C1=O mono 1 ec50 15 uM 3 Luc H3A liquid in vitro olf rtp1s rtp2 reep1 dualglo (promega) Large-Scale G Protein-Coupled ... https://doi.org/10.1021/acscen ... Table_S5
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 norm_other 0.026 30 uM 1 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1A
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 30 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_6
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_S5
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... (e)-8-Cyclohexadecen-1-one 5362739 ZGEHHVDYDNXYMW-UPHRSURJSA-N C1CCC/C=C\CCCCCCC(=O)CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... (5E)-3-methylcyclopentadec-5-en-1-one 9834606 NKMKFQCVDZVEJR-CSKARUKUSA-N CC1C/C=C/CCCCCCCCCC(=O)C1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Ambrettolide 5365703 NVIPUOMWGQAOIT-RQOWECAXSA-N C1CCCCOC(=O)CCCCC/C=C\CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... Galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.02 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 0.672 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.161 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR8B2 Q96RD0 MLARNNSLVTEFILA ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 4.791 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
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