New Database Available - Released on 23/03/2024.
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88
Unique InChIKey
5
Unique Sequence
34
EC50 Parameter
16
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR10A6 Q8NH74 100 homo sapiens MERQNQSCVVEFILL ... MERQNQSCVVEFILL ...
OR10A6 Q8NH74 99.682 homo sapiens L287P MERQNQSCVVEFILL ... MERQNQSCVVEFILL ...
OR10A6 Q8NH74 99.682 homo sapiens A117V MERQNQSCVVEFILL ... MERQNQSCVVEFILL ...
OR10A6 Q8NH74 99.363 homo sapiens V140G_L287P MERQNQSCVVEFILL ... MERQNQSCVVEFILL ...
OR10A6 Q8NH74 99.045 homo sapiens A117V_V140G_L287P MERQNQSCVVEFILL ... MERQNQSCVVEFILL ...
Experiments Pair Aggregation
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homo sapiens
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Reference Position
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 1 norm_other 30.272 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 9.001 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 1 norm_other 19.91 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.173 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 1 ec50 >1000 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 1 ec50 373 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 1 ec50 >1000 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 1 ec50 136 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 1 ec50 32 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 1 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 1 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.511 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 3.499 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 ec50 >300 900 300 300 300 900 uM 300 900 300 300 300 900 uM 3 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S4
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.32 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.344 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4B
homo sapiens OR10A6 Q8NH74 MERQNQSCVVEFILL ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4A
homo sapiens OR10A6 Q8NH74 V140G_L287P MERQNQSCVVEFILL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -6.772 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 V140G_L287P MERQNQSCVVEFILL ... butyric acid 264 107-92-6 FERIUCNNQQJTOY-UHFFFAOYSA-N CCCC(=O)O mono 1 ec50 -4.623 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 V140G_L287P MERQNQSCVVEFILL ... androstadienone 92979 4075-07-4 HNDHDMOSWUAEAW-VMXHOPILSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C ... mono 1 ec50 -4.453 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 V140G_L287P MERQNQSCVVEFILL ... isoeugenol 853433 97-54-1 BJIOGJUNALELMI-ONEGZZNKSA-N C/C=C/C1=CC(=C(C=C1)O)OC mono 1 ec50 -3.784 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 V140G_L287P MERQNQSCVVEFILL ... 3-phenyl propyl propionate 61052 122-74-7 GTNCESCYZPMXCJ-UHFFFAOYSA-N CCC(=O)OCCCC1=CC=CC=C1 mono 1 ec50 -8 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 V140G_L287P MERQNQSCVVEFILL ... 3-phenyl propyl propionate 61052 122-74-7 GTNCESCYZPMXCJ-UHFFFAOYSA-N CCC(=O)OCCCC1=CC=CC=C1 mono 1 ec50 -5.51 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 V140G_L287P MERQNQSCVVEFILL ... Nootkatone 1268142 4674-50-4 WTOYNNBCKUYIKC-JMSVASOKSA-N C[C@@H]1CC(=O)C=C2[C@]1(C[C@@H](CC2)C(=C ... mono 1 ec50 -3.841 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 A117V_V140G_L287P MERQNQSCVVEFILL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -3.677 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 A117V_V140G_L287P MERQNQSCVVEFILL ... androstenone 6852393 18339-16-7 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 1 ec50 -2.79 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR10A6 Q8NH74 A117V_V140G_L287P MERQNQSCVVEFILL ... butyric acid 264 107-92-6 FERIUCNNQQJTOY-UHFFFAOYSA-N CCCC(=O)O mono 0 ec50 n.d n.d uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
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