New Database Available - Released on 23/03/2024.
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333
Unique InChIKey
42
Unique Sequence
197
EC50 Parameter
18
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR1A1 Q9P1Q5 99.353 homo sapiens A154T_N155S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens V254T MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T277V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens R128H MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens V233M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens P285S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 98.706 homo sapiens G108A_N109K_A154T_N155S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens A106G MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens A106T MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens N109D MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens D111A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens D111S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens S112A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens G152A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens N155S MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens S248F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y250F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y251F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y251M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y258F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y258M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y276F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens Y276L MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T277M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T280A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T280F MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T280M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G108A_G152A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G108A_I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens D111A_T280A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens D111S_T280A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G152A_I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.029 homo sapiens G108A_G152A_I205V MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T99M MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 100 homo sapiens MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens G108A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens N109K MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.353 homo sapiens G108A_N109K MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens T110A MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9P1Q5 99.676 homo sapiens I114T MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
OR1A1 Q9TUA7 100 pan troglodytes MRENNQSSTLEFILL ... MRENNQSSTLEFILL ...
Experiments Pair Aggregation
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Mutation
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Molecule Name
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Reference
DOI
Reference Position
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Methoxy-3-propan-2-ylpyrazine 33166 25773-40-4 NTOPKICPEQUPPH-UHFFFAOYSA-N CC(C)C1=NC=CN=C1OC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-(Butan-2-yl)-3-methoxypyrazine 520098 24168-70-5 QMQDJVIJVPEQHE-UHFFFAOYSA-N CCC(C)C1=NC=CN=C1OC sum of isomers 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-Pyrazin-2-ylethanone 30914 22047-25-2 DBZAKQWXICEWNW-UHFFFAOYSA-N CC(=O)C1=NC=CN=C1 mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 3-Sulfanylpentan-2-one 62237 67633-97-0 SZECUQRKLXRGSJ-UHFFFAOYSA-N CCC(C(=O)C)S sum of isomers 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-sulfanylpentan-3-one 529635 17042-24-9 TWOGJUHCCNLYPC-UHFFFAOYSA-N CCC(=O)C(C)S sum of isomers 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Ethyl 3-methylsulfanylpropanoate 61592 13327-56-5 YSNWHRKJEKWJNY-UHFFFAOYSA-N CCOC(=O)CCSC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Furfurylthiol 7363 98-02-2 ZFFTZDQKIXPDAF-UHFFFAOYSA-N C1=COC(=C1)CS mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Methylfuran-3-thiol 34286 28588-74-1 RUYNUXHHUVUINQ-UHFFFAOYSA-N CC1=C(C=CO1)S mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Methyl-3-(methyldisulfanyl)furan 47649 65505-17-1 SRUTWBWLFKSTIS-UHFFFAOYSA-N CC1=C(C=CO1)SSC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Methional 18635 3268-49-3 CLUWOWRTHNNBBU-UHFFFAOYSA-N CSCCC=O mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 3-Methylthio-1-propanol 10448 505-10-2 CZUGFKJYCPYHHV-UHFFFAOYSA-N CSCCCO mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Phenylethanethiol 78126 4410-99-5 ZMRFRBHYXOQLDK-UHFFFAOYSA-N C1=CC=C(C=C1)CCS mono 1 ec50 191.69 uM 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Bis(methylsulfanyl)methane 15380 1618-26-4 LOCDPORVFVOGCR-UHFFFAOYSA-N CSCSC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Thiophen-2-ylmethanethiol 80408 6258-63-5 GCZQHDFWKVMZOE-UHFFFAOYSA-N C1=CSC(=C1)CS mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... p-Menthene-8-thiol 6427135 71159-90-5 ZQPCOAKGRYBBMR-UHFFFAOYSA-N CC1=CCC(CC1)C(C)(C)S sum of isomers 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 3-Sulfanylhexan-1-ol 521348 51755-83-0 TYZFMFVWHZKYSE-UHFFFAOYSA-N CCCC(CCO)S sum of isomers 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 3-Sulfanylhexyl acetate 518810 136954-20-6 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 1 ec50 379.94 uM 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (3-Methyl-3-sulfanylbutyl) formate 526487 50746-10-6 VTAPYUYITKYXJB-UHFFFAOYSA-N CC(C)(CCOC=O)S mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 4-Methyl-4-sulfanylpentan-2-one 88290 19872-52-7 QRNZMFDCKKEPSX-UHFFFAOYSA-N CC(=O)CC(C)(C)S mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 4-Methoxy-2-methylbutane-2-thiol 526195 94087-83-9 XVHGKKGBUDMTIQ-UHFFFAOYSA-N CC(C)(CCOC)S mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Methylsulfanylmethane 1068 75-18-3 QMMFVYPAHWMCMS-UHFFFAOYSA-N CSC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Dimethyl disulfide 12232 624-92-0 WQOXQRCZOLPYPM-UHFFFAOYSA-N CSSC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... (Methyltrisulfanyl)methane 19310 3658-80-8 YWHLKYXPLRWGSE-UHFFFAOYSA-N CSSSC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-(Methyltrisulfanyl)propane 5319765 17619-36-2 ZOYASYRPGHCQHW-UHFFFAOYSA-N CCCSSSC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-(Propyldisulfanyl)propane 12377 629-19-6 ALVPFGSHPUPROW-UHFFFAOYSA-N CCCSSCCC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 1-(Propyltrisulfanyl)propane 22383 6028-61-1 GAZXPZNJTZIGBO-UHFFFAOYSA-N CCCSSSCCC mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 3-(Methylsulfanylprop-1-ene 66282 10152-76-8 NVLPQIPTCCLBEU-UHFFFAOYSA-N CSCC=C mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Diallyl disulfide 16590 2179-57-9 PFRGXCVKLLPLIP-UHFFFAOYSA-N C=CCSSCC=C mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... Propanal 527 123-38-6 NBBJYMSMWIIQGU-UHFFFAOYSA-N CCC=O mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
homo sapiens OR1A1 Q9P1Q5 MRENNQSSTLEFILL ... 2-Methylpropanal 6561 78-84-2 AMIMRNSIRUDHCM-UHFFFAOYSA-N CC(C)C=O mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_1
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