New Database Available - Released on 23/03/2024.
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159
Unique InChIKey
24
Unique Sequence
28
EC50 Parameter
18
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR1A2 Q9Y585 100 homo sapiens MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens A108G MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens K109N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens T154A MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens R260C MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens A108G_K109N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens G256C_W293C MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens A108G_V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_T154A MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens K109N_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_V205I_T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_V205I_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_T254V_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.382 homo sapiens A108G_K109N_V205I_T254V_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
Experiments Pair Aggregation
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Reference Position
homo sapiens OR1A2 Q9Y585 T154A_S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 V205I MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 T254V MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 V277T MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... (-)-citronellal 443157 5949-05-3 NEHNMFOYXAPHSD-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CC=O mono 0 ec50 n.d n.d uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 1 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 3-Mercapto-2-methyloctan-1-ol CCCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... Musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR1A2 Q9Y585 A108G_K109N_T154A_S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 114 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 A108G_K109N_T154A MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 90 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
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