New Database Available - Released on 23/03/2024.
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183
Unique InChIKey
1
Unique Sequence
1
EC50 Parameter
18
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR1G1_OR1G2 P47890 100 homo sapiens MEGKNLTSISECFLL ... MEGKNLTSISECFLL ...
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homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 3-Mercapto-2-methyloctan-1-ol CCCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... Musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 1-hexanol 8103 ZSIAUFGUXNUGDI-UHFFFAOYSA-N CCCCCCO mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 2-ethyl-hexanol 7720 YIWUKEYIRIRTPP-UHFFFAOYSA-N CCCCC(CC)CO sum of isomers 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 1-heptanol 8129 BBMCTIGTTCKYKF-UHFFFAOYSA-N CCCCCCCO mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 1-octanol 957 KBPLFHHGFOOTCA-UHFFFAOYSA-N CCCCCCCCO mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 2-octanol 20083 SJWFXCIHNDVPSH-UHFFFAOYSA-N CCCCCCC(C)O sum of isomers 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 3-octanol 11527 NMRPBPVERJPACX-UHFFFAOYSA-N CCCCCC(CC)O sum of isomers 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 4-octanol 11515 WOFPPJOZXUTRAU-UHFFFAOYSA-N CCCCC(CCC)O sum of isomers 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 1-nonanol 8914 ZWRUINPWMLAQRD-UHFFFAOYSA-N CCCCCCCCCO mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 2-nonanol 12367 NGDNVOAEIVQRFH-UHFFFAOYSA-N CCCCCCCC(C)O sum of isomers 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 1-decanol 8174 MWKFXSUHUHTGQN-UHFFFAOYSA-N CCCCCCCCCCO mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... 1-dodecanol 8193 LQZZUXJYWNFBMV-UHFFFAOYSA-N CCCCCCCCCCCCO mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... geraniol 637566 GLZPCOQZEFWAFX-JXMROGBWSA-N CC(=CCC/C(=C/CO)/C)C mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... phenylmethanol 244 WVDDGKGOMKODPV-UHFFFAOYSA-N C1=CC=C(C=C1)CO mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... menthol 1254 NOOLISFMXDJSKH-UHFFFAOYSA-N CC1CCC(C(C1)O)C(C)C sum of isomers 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... thymol 6989 MGSRCZKZVOBKFT-UHFFFAOYSA-N CC1=CC(=C(C=C1)C(C)C)O mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... guaiacol 460 LHGVFZTZFXWLCP-UHFFFAOYSA-N COC1=CC=CC=C1O mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... maltol 8369 XPCTZQVDEJYUGT-UHFFFAOYSA-N CC1=C(C(=O)C=CO1)O mono 1 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... propionic acid 1032 XBDQKXXYIPTUBI-UHFFFAOYSA-N CCC(=O)O mono 0 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... isobutyric acid 6590 KQNPFQTWMSNSAP-UHFFFAOYSA-N CC(C)C(=O)O mono 0 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... butyric acid 264 FERIUCNNQQJTOY-UHFFFAOYSA-N CCCC(=O)O mono 0 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
homo sapiens OR1G1_OR1G2 P47890 MEGKNLTSISECFLL ... hexanoic acid 8892 FUZZWVXGSFPDMH-UHFFFAOYSA-N CCCCCC(=O)O mono 0 norm_other 10 uM 3 Ca2+ HEK gaz in vitro gα16 ca2+-sensitive fluorescent dye fluo-4 acetoxymethyl ester (molecular probes, leiden, the netherlands) rho Comparison of Odorant Specific ... https://doi.org/10.1093/chemse ... Fig_3
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