New Database Available - Released on 23/03/2024.
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130
Unique InChIKey
7
Unique Sequence
1
EC50 Parameter
16
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR2A1 Q8NGT9 100 homo sapiens MGENQTMVTEFLLLG ... MGENQTMVTEFLLLG ...
OR2A1 A0A126GVC1 100 homo sapiens MGENQTMVTEFLLLG ... MGENQTMVTEFLLLG ...
OR2A1 Q8NGT9 98.355 homo sapiens M1-_G2-_E3-_N4-_Q5-_T6-_F279S_ ... MVTEFLLLGFLLGPR ... MGENQTMVTEFLLLG ...
OR2A1 Q8NGT9 99.677 homo sapiens S168C MGENQTMVTEFLLLG ... MGENQTMVTEFLLLG ...
OR2A1 Q8NGT9 99.032 homo sapiens T73A_R74C_S168C MGENQTMVTEFLLLG ... MGENQTMVTEFLLLG ...
OR2A1 Q8NGT9 100 homo sapiens M1-_G2-_E3-_N4-_Q5-_T6- MVTEFLLLGFLLGPR ... MGENQTMVTEFLLLG ...
OR2A1 Q8NGT9 99.677 homo sapiens A157G MGENQTMVTEFLLLG ... MGENQTMVTEFLLLG ...
Experiments Pair Aggregation
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homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 S168C MGENQTMVTEFLLLG ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 T73A_R74C_S168C MGENQTMVTEFLLLG ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 S168C MGENQTMVTEFLLLG ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 T73A_R74C_S168C MGENQTMVTEFLLLG ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 S168C MGENQTMVTEFLLLG ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 T73A_R74C_S168C MGENQTMVTEFLLLG ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR2A1 Q8NGT9 S168C MGENQTMVTEFLLLG ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR2A1 Q8NGT9 T73A_R74C_S168C MGENQTMVTEFLLLG ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR2A1 Q8NGT9 S168C MGENQTMVTEFLLLG ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR2A1 Q8NGT9 T73A_R74C_S168C MGENQTMVTEFLLLG ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR2A1 Q8NGT9 S168C MGENQTMVTEFLLLG ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR2A1 Q8NGT9 T73A_R74C_S168C MGENQTMVTEFLLLG ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 3-Mercapto-2-methyloctan-1-ol CCCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... Musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR2A1 Q8NGT9 S168C MGENQTMVTEFLLLG ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR2A1 Q8NGT9 T73A_R74C_S168C MGENQTMVTEFLLLG ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 30 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_6
homo sapiens OR2A1 Q8NGT9 MGENQTMVTEFLLLG ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_S5
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