New Database Available - Released on 23/03/2024.
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148
Unique InChIKey
3
Unique Sequence
87
EC50 Parameter
19
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR51L1 Q8NGJ5 100 homo sapiens MGDWNNSDAVEPIFI ... MGDWNNSDAVEPIFI ...
OR51L1 Q8NGJ5 99.683 homo sapiens I281M MGDWNNSDAVEPIFI ... MGDWNNSDAVEPIFI ...
OR51L1 Q8NGJ5 99.365 homo sapiens T196I_A207V MGDWNNSDAVEPIFI ... MGDWNNSDAVEPIFI ...
Experiments Pair Aggregation
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Parameter
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DOI
Reference Position
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 2-methylheptanoic acid 14475 NKBWMBRPILTCRD-UHFFFAOYSA-N CCCCCC(C)C(=O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... octanoic acid 379 WWZKQHOCKIZLMA-UHFFFAOYSA-N CCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 4-ethyloctanoic acid 61840 PWKJMPFEQOHBAC-UHFFFAOYSA-N CCCCC(CC)CCC(=O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... nonanoic acid 8158 FBUKVWPVBMHYJY-UHFFFAOYSA-N CCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... decanoic acid 2969 GHVNFZFCNZKVNT-UHFFFAOYSA-N CCCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... undecanoic acid 8180 ZDPHROOEEOARMN-UHFFFAOYSA-N CCCCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... benzoic acid 243 WPYMKLBDIGXBTP-UHFFFAOYSA-N C1=CC=C(C=C1)C(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... phenylacetic acid 999 WLJVXDMOQOGPHL-UHFFFAOYSA-N C1=CC=C(C=C1)CC(=O)O mono 1 ec50 11.482 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.455 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 1.946 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.271 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 3.041 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 1.689 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.24 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... Butter aroma recombinate (diacetyl, butanoic acid, delta-decalactone) QSJXEFYPDANLFS-UHFFFAOYSA-N FE ... CC(=O)C(=O)C CCCC(=O)O CCCCCC1CCCC(=O)O1 mixture 0 norm_pair 4 41 29 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.686 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.58 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.248 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 5.171 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 ec50 n.d n.d 3000 uM 3 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S6
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4B
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4A
homo sapiens OR51L1 Q8NGJ5 I281M MGDWNNSDAVEPIFI ... n-amyl acetate 12348 628-63-7 PGMYKACGEOXYJE-UHFFFAOYSA-N CCCCCOC(=O)C mono 0 norm_other -0.084 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR51L1 Q8NGJ5 I281M MGDWNNSDAVEPIFI ... Cyclohexanone 7967 108-94-1 JHIVVAPYMSGYDF-UHFFFAOYSA-N C1CCC(=O)CC1 mono 0 norm_other -0.083 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR51L1 Q8NGJ5 I281M MGDWNNSDAVEPIFI ... 2-heptanone 8051 110-43-0 CATSNJVOTSVZJV-UHFFFAOYSA-N CCCCCC(=O)C mono 0 norm_other -0.049 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR51L1 Q8NGJ5 I281M MGDWNNSDAVEPIFI ... acetophenone 7410 98-86-2 KWOLFJPFCHCOCG-UHFFFAOYSA-N CC(=O)C1=CC=CC=C1 mono 0 norm_other 0.063 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
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