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80
Unique InChIKey
2
Unique Sequence
0
EC50 Parameter
14
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR52E4 Q8NGH9 100 homo sapiens MPSINDTHFYPPFFL ... MPSINDTHFYPPFFL ...
OR52E4 Q8NGH9 99.038 homo sapiens V176I_R184M_R228H MPSINDTHFYPPFFL ... MPSINDTHFYPPFFL ...
Experiments Pair Aggregation
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homo sapiens
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UniProt ID
Mutation
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Molecule Name
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InChIKey
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Unit
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Nbr. measurements
Type
Cell_line
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Assay
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Co-transfection
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Tag
Reference
DOI
Reference Position
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... (5E)-3-methylcyclopentadec-5-en-1-one 9834606 NKMKFQCVDZVEJR-CSKARUKUSA-N CC1C/C=C/CCCCCCCCCC(=O)C1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... Ambrettolide 5365703 NVIPUOMWGQAOIT-RQOWECAXSA-N C1CCCCOC(=O)CCCCC/C=C\CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... Galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.051 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 2.112 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 0.938 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 3.528 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 1.529 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.149 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... Butter aroma recombinate (diacetyl, butanoic acid, delta-decalactone) QSJXEFYPDANLFS-UHFFFAOYSA-N FE ... CC(=O)C(=O)C CCCC(=O)O CCCCCC1CCCC(=O)O1 mixture 0 norm_pair 4 41 29 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.723 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.618 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.868 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52E4 Q8NGH9 MPSINDTHFYPPFFL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.165 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
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