New Database Available - Released on 23/03/2024.
93
Unique InChIKey
4
Unique Sequence
24
EC50 Parameter
15
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR52L1 Q8NGH7 98.48 homo sapiens D88N_C140R_C161R_K183T_W297R MTLVSFFSFLSKPLI ... MTLVSFFSFLSKPLI ...
OR52L1 Q8NGH7 98.784 homo sapiens C140R_C161R_K183T_W297R MTLVSFFSFLSKPLI ... MTLVSFFSFLSKPLI ...
OR52L1 Q8NGH7 100 homo sapiens MTLVSFFSFLSKPLI ... MTLVSFFSFLSKPLI ...
OR52L1 Q8NGH7 99.696 homo sapiens D88N MTLVSFFSFLSKPLI ... MTLVSFFSFLSKPLI ...
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homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 1.139 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.039 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 2.989 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 2.089 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 0.751 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... Butter aroma recombinate (diacetyl, butanoic acid, delta-decalactone) QSJXEFYPDANLFS-UHFFFAOYSA-N FE ... CC(=O)C(=O)C CCCC(=O)O CCCCCC1CCCC(=O)O1 mixture 1 norm_pair 4 41 29 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... Butter aroma recombinate (diacetyl, butanoic acid, delta-decalactone) QSJXEFYPDANLFS-UHFFFAOYSA-N FE ... CC(=O)C(=O)C CCCC(=O)O CCCCCC1CCCC(=O)O1 mixture 1 ec50 15.8 Fold 30 Fold 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_5
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.911 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.673 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 4.957 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 ec50 n.d n.d 300 900 300 300 300 900 uM 3 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S5
homo sapiens OR52L1 Q8NGH7 MTLVSFFSFLSKPLI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.998 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR52L1 Q8NGH7 D88N MTLVSFFSFLSKPLI ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3