New Database Available - Released on 23/03/2024.
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121
Unique InChIKey
6
Unique Sequence
62
EC50 Parameter
16
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR5AN1 Q8NGI8 99.678 homo sapiens L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 99.357 homo sapiens C142Y_L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 100 homo sapiens MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 A0A6D2VXZ9 66.558 pongo abelii G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... MTGGGNITEITYFIL ...
OR5AN1 A0A6D2VXZ9 100 pongo abelii MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 A0A2J8LCK1 67.208 pan troglodytes W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... MTWGGNITEITYFIL ...
Experiments Pair Aggregation
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Responsive
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Parameter
norm_other
ec50
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Species
homo sapiens
pan troglodytes
pongo abelii
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Species
Gene Name
UniProt ID
Mutation
Sequence
Molecule Name
CID
CAS
InChIKey
SMILES
Mixture
Responsive
Parameter
Value
Unit
Concentration
Concentration Unit
Nbr. measurements
Type
Cell_line
Delivery
Assay
Gprotein
Co-transfection
Assay System
Tag
Reference
DOI
Reference Position
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Muscone 10947 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 1 ec50 39.811 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Ethylene brassylate 61014 XRHCAGNSDHCHFJ-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCCC1 mono 1 ec50 501.187 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Cosmone 54543965 ZFGBKXBPHOUSJX-UHFFFAOYSA-N CC1CC=CCCCCCCCCC(=O)C1 sum of isomers 1 ec50 2.512 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Musk MC4 41270 GJJSUPSPZIZYPM-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCC1 mono 1 ec50 12.589 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Muscenone 54116156 NKMKFQCVDZVEJR-UHFFFAOYSA-N CC1CC=CCCCCCCCCCC(=O)C1 sum of isomers 1 ec50 1.585 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Thibetolide 235414 FKUPPRZPSYCDRS-UHFFFAOYSA-N C1CCCCCCCOC(=O)CCCCCC1 mono 1 ec50 19.953 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Velvione 5362736 ABRIMXGLNHCLIP-VURMDHGXSA-N C1CCCCCC(=O)CCC/C=C\CCCC1 mono 1 ec50 5.012 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Cyclopentadecanone 10409 OSOIQJGOYGSIMF-UHFFFAOYSA-N C1CCCCCCCC(=O)CCCCCC1 mono 1 ec50 7.943 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Nirvanolide 11064468 NUSRNVWNTPMBJA-VURMDHGXSA-N CC1CCOC(=O)CCCCCCC/C=C\C1 mono 1 ec50 158.489 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Helvetolide 16063567 LSTSBZKIQFOPHA-UHFFFAOYSA-N CCC(=O)OCC(C)(C)OC(C)C1CCCC(C1)(C)C sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Serenolide 12022011 BZLYOWSSNHNYKW-UHFFFAOYSA-N CC(C1CCCC(C1)(C)C)OC(C)(C)COC(=O)C2CC2 sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Sylkolide 11277198 ZYIJXTQXQNXPSH-FMIVXFBMSA-N CC(C)/C=C(\C)/C(C)OC(C)(C)COC(=O)C1CC1 mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 1-(3,3-dimethylcyclohexyl)ethyl acetate 91339 YWVSYRJWCROMKO-UHFFFAOYSA-N CC(C1CCCC(C1)(C)C)OC(=O)C sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... musk xylene 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 1 ec50 4.2 uM 17 Luc HEK liquid in vitro hrtp1s/hrtp2 Human olfactory receptors deor ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.227 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 1.659 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.047 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 3.663 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 1.984 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 0.962 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.326 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.281 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.09 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.625 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
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