New Database Available - Released on 23/03/2024.
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201
Unique InChIKey
3
Unique Sequence
6
EC50 Parameter
11
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR5M3 Q8NGP4 99.674 homo sapiens L84F MLNFTDVTEFILLGL ... MLNFTDVTEFILLGL ...
OR5M3 Q8NGP4 100 homo sapiens MLNFTDVTEFILLGL ... MLNFTDVTEFILLGL ...
OR5M3 Q8NGP4 99.349 homo sapiens N3Y_A156T MLYFTDVTEFILLGL ... MLNFTDVTEFILLGL ...
Experiments Pair Aggregation
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Type
Cell_line
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Tag
Reference
DOI
Reference Position
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Pent-1-en-3-one 15394 JLIDVCMBCGBIEY-UHFFFAOYSA-N CCC(=O)C=C mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Pentan-2,3-dione 11747 TZMFJUDUGYTVRY-UHFFFAOYSA-N CCC(=O)C(=O)C mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Pentanoic acid 7991 NQPDZGIKBAWPEJ-UHFFFAOYSA-N CCCCC(=O)O mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Phenylacetaldehyde 998 DTUQWGWMVIHBKE-UHFFFAOYSA-N C1=CC=C(C=C1)CC=O mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Thiophen-2-ylmethanethiol 80408 GCZQHDFWKVMZOE-UHFFFAOYSA-N C1=CSC(=C1)CS mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... methyl cinnamate 637520 CCRCUPLGCSFEDV-BQYQJAHWSA-N COC(=O)/C=C/C1=CC=CC=C1 mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Nonan-1-ol 8914 ZWRUINPWMLAQRD-UHFFFAOYSA-N CCCCCCCCCO mono 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 3-Mercapto-2-methyloctan-1-ol CCCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 30 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_6
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 300 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_S5
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... (e)-8-Cyclohexadecen-1-one 5362739 ZGEHHVDYDNXYMW-UPHRSURJSA-N C1CCC/C=C\CCCCCCC(=O)CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... (5E)-3-methylcyclopentadec-5-en-1-one 9834606 NKMKFQCVDZVEJR-CSKARUKUSA-N CC1C/C=C/CCCCCCCCCC(=O)C1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Ambrettolide 5365703 NVIPUOMWGQAOIT-RQOWECAXSA-N C1CCCCOC(=O)CCCCC/C=C\CCC1 mono 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... Galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 0.562 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 0.816 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 6.043 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 2.968 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.171 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5M3 Q8NGP4 MLNFTDVTEFILLGL ... 2-Ethyl-3,5(6)-dimethylpyrazine, sum of isomers JZBCTZLGKSYRSF-UHFFFAOYSA-N WH ... CCC1=NC=C(N=C1C)C CCC1=NC(=CN=C1C)C mixture 0 norm_pair 300 uM 3 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_3
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