New Database Available - Released on 23/03/2024.
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127
Unique InChIKey
2
Unique Sequence
2
EC50 Parameter
14
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR2W3_OR2W3P_OR2W8P Q7Z3T1 100 homo sapiens MDGTNGSTQTHFILL ... MDGTNGSTQTHFILL ...
OR2W3_OR2W3P_OR2W8P Q7Z3T1 96.166 homo sapiens E196D_A300G_L301T_R303K_L304V_ ... MDGTNGSTQTHFILL ... MDGTNGSTQTHFILL ...
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homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... nerol 643820 106-25-2 GLZPCOQZEFWAFX-YFHOEESVSA-N CC(=CCC/C(=C\CO)/C)C mono 0 norm_other 800 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S1
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... heptanoic acid 8094 111-14-8 MNWFXJYAOYHMED-UHFFFAOYSA-N CCCCCCC(=O)O mono 0 norm_other 100 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... heptanoic acid 8094 111-14-8 MNWFXJYAOYHMED-UHFFFAOYSA-N CCCCCCC(=O)O mono 0 norm_other 200 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... heptanoic acid 8094 111-14-8 MNWFXJYAOYHMED-UHFFFAOYSA-N CCCCCCC(=O)O mono 0 norm_other 400 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... heptanoic acid 8094 111-14-8 MNWFXJYAOYHMED-UHFFFAOYSA-N CCCCCCC(=O)O mono 0 norm_other 600 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... heptanoic acid 8094 111-14-8 MNWFXJYAOYHMED-UHFFFAOYSA-N CCCCCCC(=O)O mono 0 norm_other 800 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... octanoic acid 379 124-07-2 WWZKQHOCKIZLMA-UHFFFAOYSA-N CCCCCCCC(=O)O mono 0 norm_other 150 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... octanoic acid 379 124-07-2 WWZKQHOCKIZLMA-UHFFFAOYSA-N CCCCCCCC(=O)O mono 0 norm_other 200 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... octanoic acid 379 124-07-2 WWZKQHOCKIZLMA-UHFFFAOYSA-N CCCCCCCC(=O)O mono 0 norm_other 400 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... octanoic acid 379 124-07-2 WWZKQHOCKIZLMA-UHFFFAOYSA-N CCCCCCCC(=O)O mono 0 norm_other 600 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... octanoic acid 379 124-07-2 WWZKQHOCKIZLMA-UHFFFAOYSA-N CCCCCCCC(=O)O mono 0 norm_other 800 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... farnesol 445070 4602-84-0 CRDAMVZIKSXKFV-YFVJMOTDSA-N CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C mono 0 ec50 n.d n.d 1000 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S6
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 3-Mercapto-2-methyloctan-1-ol CCCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... Musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... Androstenone 6852393 HFVMLYAGWXSTQI-QYXZOKGRSA-N C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... mono 0 norm_other 0.014 30 uM 1 Luc H3A liquid in vitro olf rtp1s ric8b dual-glo luciferase rho Keller, A., Zhuang, H., Chi, Q ... https://doi.org/10.1038/nature ... Fig_1A
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR2W3_OR2W3P_OR2W8P Q7Z3T1 MDGTNGSTQTHFILL ... 3-Methyl-2,4-nonanedione 529481 BGVBGAIWXAXBLP-UHFFFAOYSA-N CCCCCC(=O)C(C)C(=O)C sum of isomers 0 norm_rec 30 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho The Broadly Tuned Odorant Rece ... https://doi.org/10.1093/chemse ... Fig_6
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