New Database Available - Released on 23/03/2024.
123
Unique InChIKey
3
Unique Sequence
1
EC50 Parameter
14
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR51B5 Q9H339 100 homo sapiens MSSSGSSHPFLLTGF ... MSSSGSSHPFLLTGF ...
OR51B5 Q9H339 99.038 homo sapiens G5S_R194Q_L220F MSSSSSSHPFLLTGF ... MSSSGSSHPFLLTGF ...
OR51B5 Q9H339 99.038 homo sapiens G5S_I102T_P160L MSSSSSSHPFLLTGF ... MSSSGSSHPFLLTGF ...
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UniProt ID
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DOI
Reference Position
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... dodecanoic acid 3893 143-07-7 POULHZVOKOAJMA-UHFFFAOYSA-N CCCCCCCCCCCC(=O)O mono 1 norm_other 400 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_2B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... dodecanoic acid 3893 143-07-7 POULHZVOKOAJMA-UHFFFAOYSA-N CCCCCCCCCCCC(=O)O mono 1 norm_other 600 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_2B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... farnesol 445070 4602-84-0 CRDAMVZIKSXKFV-YFVJMOTDSA-N CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C mono 1 norm_other 200 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_2B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... farnesol 445070 4602-84-0 CRDAMVZIKSXKFV-YFVJMOTDSA-N CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C mono 1 norm_other 400 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_2B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... farnesol 445070 4602-84-0 CRDAMVZIKSXKFV-YFVJMOTDSA-N CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C mono 1 norm_other 600 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_2B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... farnesol 445070 4602-84-0 CRDAMVZIKSXKFV-YFVJMOTDSA-N CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C mono 1 norm_other 800 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_2B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... farnesol 445070 4602-84-0 CRDAMVZIKSXKFV-YFVJMOTDSA-N CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C mono 1 norm_other 1000 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_2B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... farnesol 445070 4602-84-0 CRDAMVZIKSXKFV-YFVJMOTDSA-N CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C mono 1 ec50 180 uM 1000 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_3C
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 0 norm_other 200 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 0 norm_other 400 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 0 norm_other 600 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 0 norm_other 800 uM 3 GFP Yeast liquid in vitro millipore guava easycyte ht flow cytometer Rapid deorphanization of human ... https://doi.org/10.1021/acs.bi ... Figure_S2
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... 3-Mercapto-2-methyloctan-1-ol CCCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... Musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... Diacetyl 650 QSJXEFYPDANLFS-UHFFFAOYSA-N CC(=O)C(=O)C mono 0 norm_pair 4 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... butanoic acid 264 FERIUCNNQQJTOY-UHFFFAOYSA-N CCCC(=O)O mono 0 norm_pair 41 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR51B5 Q9H339 MSSSGSSHPFLLTGF ... Delta-decalactone 12810 GHBSPIPJMLAMEP-UHFFFAOYSA-N CCCCCC1CCCC(=O)O1 sum of isomers 0 norm_pair 29 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4