New Database Available - Released on 23/03/2024.
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152
Unique InChIKey
4
Unique Sequence
117
EC50 Parameter
19
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR51E1_OR51E1P_OR52A3P Q8TCB6 99.685 homo sapiens +1M_S11N MMVDPNGNESNATYF ... MVDPNGNESSATYFI ...
OR51E1_OR51E1P_OR52A3P Q8TCB6 99.685 homo sapiens K298R MVDPNGNESSATYFI ... MVDPNGNESSATYFI ...
OR51E1_OR51E1P_OR52A3P Q8TCB6 100 homo sapiens +1M MMVDPNGNESSATYF ... MVDPNGNESSATYFI ...
OR51E1_OR51E1P_OR52A3P Q8TCB6 100 homo sapiens MVDPNGNESSATYFI ... MVDPNGNESSATYFI ...
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homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... 4-ethyloctanoic acid 61840 PWKJMPFEQOHBAC-UHFFFAOYSA-N CCCCC(CC)CCC(=O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... nonanoic acid 8158 FBUKVWPVBMHYJY-UHFFFAOYSA-N CCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... decanoic acid 2969 GHVNFZFCNZKVNT-UHFFFAOYSA-N CCCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... undecanoic acid 8180 ZDPHROOEEOARMN-UHFFFAOYSA-N CCCCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... benzoic acid 243 WPYMKLBDIGXBTP-UHFFFAOYSA-N C1=CC=C(C=C1)C(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... phenylacetic acid 999 WLJVXDMOQOGPHL-UHFFFAOYSA-N C1=CC=C(C=C1)CC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... 5-norbornene-2-carboxylic acid 78949 FYGUSUBEMUKACF-UHFFFAOYSA-N C1C2CC(C1C=C2)C(=O)O sum of isomers 1 ec50 18 uM 19 Luc HEK liquid in vitro hrtp1s/hrtp2 Human olfactory receptors deor ... https://doi.org/10.1093/chemse ... Figure_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.025 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 1.576 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.182 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 2.943 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 1.895 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.369 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... Butter aroma recombinate (diacetyl, butanoic acid, delta-decalactone) QSJXEFYPDANLFS-UHFFFAOYSA-N FE ... CC(=O)C(=O)C CCCC(=O)O CCCCCC1CCCC(=O)O1 mixture 0 norm_pair 4 41 29 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 3.681 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 ec50 n.d n.d 300 900 300 300 300 900 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S3
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.173 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.59 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.756 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 +1M MMVDPNGNESSATYF ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 1 ec50 -3.408 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 +1M_S11N MMVDPNGNESNATYF ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 1 ec50 -4.711 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 +1M_S11N MMVDPNGNESNATYF ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 1 ec50 -4.32 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 K298R MVDPNGNESSATYFI ... isovaleric acid 10430 503-74-2 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 1 ec50 -5.383 log(M) uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 +1M MMVDPNGNESSATYF ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 +1M MMVDPNGNESSATYF ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4B
homo sapiens OR51E1_OR51E1P_OR52A3P Q8TCB6 MVDPNGNESSATYFI ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4A
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