New Database Available - Released on 23/03/2024.
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148
Unique InChIKey
3
Unique Sequence
87
EC50 Parameter
19
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR51L1 Q8NGJ5 99.365 homo sapiens T196I_A207V MGDWNNSDAVEPIFI ... MGDWNNSDAVEPIFI ...
OR51L1 Q8NGJ5 100 homo sapiens MGDWNNSDAVEPIFI ... MGDWNNSDAVEPIFI ...
OR51L1 Q8NGJ5 99.683 homo sapiens I281M MGDWNNSDAVEPIFI ... MGDWNNSDAVEPIFI ...
Experiments Pair Aggregation
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homo sapiens
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UniProt ID
Mutation
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Molecule Name
CID
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SMILES
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Responsive
Parameter
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Unit
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Nbr. measurements
Type
Cell_line
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Gprotein
Co-transfection
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Tag
Reference
DOI
Reference Position
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... Galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 0 norm_other 100 uM 2 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Diverse yet selective tuning o ... https://doi.org/10.21203/rs.3. ... Figure_S1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... acetic acid 176 QTBSBXVTEAMEQO-UHFFFAOYSA-N CC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... propanoic acid 1032 XBDQKXXYIPTUBI-UHFFFAOYSA-N CCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... butanoic acid 264 FERIUCNNQQJTOY-UHFFFAOYSA-N CCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... isovaleric acid 10430 GWYFCOCPABKNJV-UHFFFAOYSA-N CC(C)CC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... pentanoic acid 7991 NQPDZGIKBAWPEJ-UHFFFAOYSA-N CCCCC(=O)O mono 1 ec50 363.078 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... hexanoic acid 8892 FUZZWVXGSFPDMH-UHFFFAOYSA-N CCCCCC(=O)O mono 1 ec50 93.325 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 2-methylhexanoic acid 20653 CVKMFSAVYPAZTQ-UHFFFAOYSA-N CCCCC(C)C(=O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 3-methylhexanoic acid 95315 NZQMQVJXSRMTCJ-UHFFFAOYSA-N CCCC(C)CC(=O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... (E)-3-methyl-2-hexenoic acid 6443739 NTWSIWWJPQHFTO-AATRIKPKSA-N CCC/C(=C/C(=O)O)/C mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 3-hydroxy-3-methylhexanoic acid 16666688 RGRNSTGIHROKJB-UHFFFAOYSA-N CCCC(C)(CC(=O)O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... heptanoic acid 8094 MNWFXJYAOYHMED-UHFFFAOYSA-N CCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 2-methylheptanoic acid 14475 NKBWMBRPILTCRD-UHFFFAOYSA-N CCCCCC(C)C(=O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... octanoic acid 379 WWZKQHOCKIZLMA-UHFFFAOYSA-N CCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... 4-ethyloctanoic acid 61840 PWKJMPFEQOHBAC-UHFFFAOYSA-N CCCCC(CC)CCC(=O)O sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... nonanoic acid 8158 FBUKVWPVBMHYJY-UHFFFAOYSA-N CCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... decanoic acid 2969 GHVNFZFCNZKVNT-UHFFFAOYSA-N CCCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... undecanoic acid 8180 ZDPHROOEEOARMN-UHFFFAOYSA-N CCCCCCCCCCC(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... benzoic acid 243 WPYMKLBDIGXBTP-UHFFFAOYSA-N C1=CC=C(C=C1)C(=O)O mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... phenylacetic acid 999 WLJVXDMOQOGPHL-UHFFFAOYSA-N C1=CC=C(C=C1)CC(=O)O mono 1 ec50 11.482 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Veithen, Alex, et al. "Identif ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.455 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 1.946 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.271 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 3.041 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 1.689 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.24 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... Butter aroma recombinate (diacetyl, butanoic acid, delta-decalactone) QSJXEFYPDANLFS-UHFFFAOYSA-N FE ... CC(=O)C(=O)C CCCC(=O)O CCCCCC1CCCC(=O)O1 mixture 0 norm_pair 4 41 29 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1-s pglosensor-22f-camp (promega) rho A Butter Aroma Recombinate Act ... https://doi.org/10.1021/acs.ja ... Fig_4
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR51L1 Q8NGJ5 MGDWNNSDAVEPIFI ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.686 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
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