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111
Unique InChIKey
5
Unique Sequence
33
EC50 Parameter
19
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR5A1_OR5A1P Q8NGJ0 99.676 homo sapiens I52V_R310-_K311-_K312-_V313-_F ... MSITKAWNSSSVTMF ... MSITKAWNSSSVTMF ...
OR5A1_OR5A1P Q8NGJ0 99.683 homo sapiens I52T MSITKAWNSSSVTMF ... MSITKAWNSSSVTMF ...
OR5A1_OR5A1P Q8NGJ0 98.077 homo sapiens I16N_I52V_L197H_R310S_K311G_K3 ... MSITKAWNSSSVTMF ... MSITKAWNSSSVTMF ...
OR5A1_OR5A1P Q8NGJ0 99.683 homo sapiens D183N MSITKAWNSSSVTMF ... MSITKAWNSSSVTMF ...
OR5A1_OR5A1P Q8NGJ0 100 homo sapiens MSITKAWNSSSVTMF ... MSITKAWNSSSVTMF ...
Experiments Pair Aggregation
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Reference Position
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.668 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.014 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.534 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.194 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.73 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4B
homo sapiens OR5A1_OR5A1P Q8NGJ0 MSITKAWNSSSVTMF ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4A
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR5A1_OR5A1P Q8NGJ0 D183N MSITKAWNSSSVTMF ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
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