New Database Available - Released on 23/03/2024.
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230
Unique InChIKey
2
Unique Sequence
18
EC50 Parameter
16
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR8H1 F6TM11 100 equus caballus MNRRNNTNLPDFILI ... MNRRNNTNLPDFILI ...
OR8H1 Q8NGG4 100 homo sapiens MGRRNNTNVPDFILT ... MGRRNNTNVPDFILT ...
Experiments Pair Aggregation
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homo sapiens
equus caballus
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UniProt ID
Mutation
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Molecule Name
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Nbr. measurements
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Reference
DOI
Reference Position
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 6.48 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 1.522 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 1 ec50 >1000 uM 1000 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 1 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 4.466 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 ec50 n.d n.d 300 900 300 300 300 900 uM 3 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_S3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 1 norm_other 2.574 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.437 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.467 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 1 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 1 ec50 32.02 uM 500 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure2
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (+)-Sabinene 10887971 2009-00-9 NDVASEGYNIMXJL-NXEZZACHSA-N CC(C)[C@]12CCC(=C)[C@H]1C2 mono 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (+/-)-α-Pinene 6654 80-56-8 GRWFGVWFFZKLTI-UHFFFAOYSA-N CC1=CCC2CC1C2(C)C sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (+/-)-α-Terpineol, sum of isomers 17100 98-55-5 WUOACPNHFRMFPN-UHFFFAOYSA-N CC1=CCC(CC1)C(C)(C)O sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (+/-)-β-Pinene, sum of isomers 14896 127-91-3 WTARULDDTDQWMU-UHFFFAOYSA-N CC1(C2CCC(=C)C1C2)C sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (1R/1S)-1,3,3-Trimethylbicyclo[2.2.1]heptan-2-one (fenchone), sum of isomers 14525 1195-79-5 LHXDLQBQYFFVNW-UHFFFAOYSA-N CC1(C2CCC(C2)(C1=O)C)C sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2E)-1-(2,6,6-trimethylcyclohex-1-en-1-yl)But-2-en-1-one (E-β-damascone) 5374527 23726-91-2 BGTBFNDXYDYBEY-FNORWQNLSA-N C/C=C/C(=O)C1=C(CCCC1(C)C)C mono 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2E,5R/5S)-5-Methylhept-2-en-4-one (filbertone), sum of isomers 5362588 102322-83-8 ARJWAURHQDJJAC-GQCTYLIASA-N CCC(C)C(=O)/C=C/C mono 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2E,6Z)-2,6-Nonadienal 643731 26370-28-5 HZYHMHHBBBSGHB-ODYTWBPASA-N CC/C=C\CC/C=C/C=O mono 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2E,6Z)-Nona-2,6-dien-1-ol 5362833 28069-72-9 AMXYRHBJZOVHOL-ODYTWBPASA-N CC/C=C\CC/C=C/CO mono 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2R/2S)-2-Methylbutan-1-ol, sum of isomers 8723 137-32-6 QPRQEDXDYOZYLA-UHFFFAOYSA-N CCC(C)CO sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2R/2S)-2-Methylbutylacetate, sum of isomers 12209 624-41-9 XHIUFYZDQBSEMF-UHFFFAOYSA-N CCC(C)COC(=O)C sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2R/2S)-2-Sulfanylpetan-3-one, sum of isomers 529635 17042-24-9 TWOGJUHCCNLYPC-UHFFFAOYSA-N CCC(=O)C(C)S sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2R/2S)-4-Methoxy-2,5-dimethylfuran-3(2H)-one, sum of isomers 61325 4077-47-8 SIMKGHMLPVDSJE-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)OC sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2R/2S,3R/3S)-2-Methyl-3-sulfanylpentan-1-ol, sum of isomers 6430888 227456-27-1 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (2S,4R)/(2R,4S)-4-Methyl-2-(2-methylrop-1-en-1-yl)tetrahydro-2H-pyran((+/-)-cis-rose oxide), sum of isomers 27866 16409-43-1 CZCBTSFUTPZVKJ-UHFFFAOYSA-N CC1CCOC(C1)C=C(C)C sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (3E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)But-3-en-2-one (β-ionone) 638014 79-77-6 PSQYTAPXSHCGMF-BQYQJAHWSA-N CC1=C(C(CCC1)(C)C)/C=C/C(=O)C mono 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
homo sapiens OR8H1 Q8NGG4 MGRRNNTNVPDFILT ... (3R/3S)-3-Hydroxybutan-2-one, sum of isomers 179 513-86-0 ROWKJAVDOGWPAT-UHFFFAOYSA-N CC(C(=O)C)O sum of isomers 0 norm_pair 300 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure3
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