157
Unique InChIKey
23
Unique Sequence
28
EC50 Parameter
15
Unique DOI
BLAST
OR1A2 | Q9Y585 | 100 | homo sapiens | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | ||
OR1A2 | Q9Y585 | 99.676 | homo sapiens | A108G | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.676 | homo sapiens | K109N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.676 | homo sapiens | V205I | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.676 | homo sapiens | T254V | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.676 | homo sapiens | V277T | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.676 | homo sapiens | T154A | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.676 | homo sapiens | S155N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.353 | homo sapiens | A108G_K109N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.353 | homo sapiens | T154A_S155N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.353 | homo sapiens | G256C_W293C | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.353 | homo sapiens | A108G_V205I | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.029 | homo sapiens | A108G_K109N_T154A | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.029 | homo sapiens | A108G_K109N_S155N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.029 | homo sapiens | A108G_T154A_S155N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.029 | homo sapiens | K109N_T154A_S155N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.029 | homo sapiens | A108G_K109N_V205I | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 99.029 | homo sapiens | A108G_K109N_T254V | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 98.706 | homo sapiens | A108G_K109N_T154A_S155N | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 98.706 | homo sapiens | A108G_K109N_V205I_T254V | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 98.706 | homo sapiens | A108G_K109N_V205I_V277T | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 98.706 | homo sapiens | A108G_K109N_T254V_V277T | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... | |
OR1A2 | Q9Y585 | 98.382 | homo sapiens | A108G_K109N_V205I_T254V_V277T | MKKENQSFNLDFILL ... | MKKENQSFNLDFILL ... |
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homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | Sotolone | 62835 | UNYNVICDCJHOPO-UHFFFAOYSA-N | CC1C(=C(C(=O)O1)O)C | sum of isomers | 0 | norm_rec | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s | glosensor (promega) | il-6-halotag | Key food furanones furaneol an ... | https://doi.org/10.1021/acs.ja ... | Figure_1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | homofuraneol | 33931 | GWCRPYGYVRXVLI-UHFFFAOYSA-N | CCC1C(=O)C(=C(O1)C)O | sum of isomers | 0 | norm_rec | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s | glosensor (promega) | il-6-halotag | Key food furanones furaneol an ... | https://doi.org/10.1021/acs.ja ... | Figure_1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 3-mercapto-2-methylpentan-1-ol | 6430888 | HABNNYNSJFKZFE-UHFFFAOYSA-N | CCC(C(C)CO)S | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_S1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | Abhexone | 61199 | IUFQZPBIRYFPFD-UHFFFAOYSA-N | CCC1C(=C(C(=O)O1)O)C | sum of isomers | 0 | norm_rec | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s | glosensor (promega) | il-6-halotag | Key food furanones furaneol an ... | https://doi.org/10.1021/acs.ja ... | Figure_1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | Allyl Phenyl acetate | 15717 | 1746-13-0 | ZCDYAMJXVAUTIM-UHFFFAOYSA-N | C=CCOC(=O)CC1=CC=CC=C1 | mono | 0 | norm_rec | 100 | uM | 2 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | il-6-halotag | IL-6–HaloTag® enables live- ... | https://doi.org/10.14440/jbm.2 ... | Figure_5 | |||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 2,3,5-Trimethylpyrazine | 26808 | 14667-55-1 | IAEGWXHKWJGQAZ-UHFFFAOYSA-N | CC1=CN=C(C(=N1)C)C | mono | 0 | norm_rec | 100 | uM | 3 | Luc | HEK | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | il-6-halotag | An evolutionary conserved olfa ... | https://doi.org/10.1096/fj.202 ... | Figure_1A | |||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 2,4,5-trimethyl-4,5-dihydrothiazole | 263626 | 4145-93-1 | CIEKNJJOENYFQL-UHFFFAOYSA-N | CC1C(SC(=N1)C)C | sum of isomers | 0 | norm_rec | 100 | uM | 3 | Luc | HEK | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | il-6-halotag | An evolutionary conserved olfa ... | https://doi.org/10.1096/fj.202 ... | Figure_1B | |||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 2-methyl-3-sulfanylpropan-1-ol | 529079 | FCIVYWQHILCTLI-UHFFFAOYSA-N | CC(CO)CS | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_3E | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 2-Methyl-3-sulfanylheptan-1-ol | 21997288 | OCZSUTGSYBERRF-UHFFFAOYSA-N | CCCCC(C(C)CO)S | sum of isomers | 1 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_3E | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 3-Mercapto-2-methyloctan-1-ol | CCCCCC(C(C)CO)S | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | NxG108CC15 | liquid | in vitro | olf | gγ13 rtp1s | glosensor (promega) | rho | OR2M3: a highly specific and n ... | https://doi.org/10.1093/chemse ... | Figure_3E | ||||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | (+/-)-Muscone | 10947 | 541-91-3 | ALHUZKCOMYUFRB-UHFFFAOYSA-N | CC1CCCCCCCCCCCCC(=O)C1 | sum of isomers | 0 | norm_other | 0 | 100 | uM | 3 | Luc | HEK | liquid | in vitro | rtp1s-pme18s | dual-glo luciferase assay system | flag | Ligand specificity and evoluti ... | https://doi.org/10.1523/JNEURO ... | Figure_4A | |||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | Musk xylol | 62329 | XMWRWTSZNLOZFN-UHFFFAOYSA-N | CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... | mono | 0 | norm_other | 0 | 100 | uM | 3 | Luc | HEK | liquid | in vitro | rtp1s-pme18s | dual-glo luciferase assay system | flag | Ligand specificity and evoluti ... | https://doi.org/10.1523/JNEURO ... | Figure_4A | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | musk ketone | 6669 | WXCMHFPAUCOJIG-UHFFFAOYSA-N | CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... | mono | 0 | norm_other | 0 | 100 | uM | 3 | Luc | HEK | liquid | in vitro | rtp1s-pme18s | dual-glo luciferase assay system | flag | Ligand specificity and evoluti ... | https://doi.org/10.1523/JNEURO ... | Figure_4A | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | (R)-(-)-Carvone | 439570 | ULDHMXUKGWMISQ-SECBINFHSA-N | CC1=CC[C@H](CC1=O)C(=C)C | mono | 0 | ec50 | n.d | n.d | 2000 | uM | 3 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor-22f | rho | C. Geithe, J. Protze, F. Kreuc ... | https://doi.org/10.1007/s00018 ... | Fig_2C | ||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | (S)-(+)-Carvone | 16724 | ULDHMXUKGWMISQ-VIFPVBQESA-N | CC1=CC[C@@H](CC1=O)C(=C)C | mono | 0 | ec50 | n.d | n.d | 2000 | uM | 3 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor-22f | rho | C. Geithe, J. Protze, F. Kreuc ... | https://doi.org/10.1007/s00018 ... | Fig_2C | ||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | Androstenone | 6852393 | HFVMLYAGWXSTQI-QYXZOKGRSA-N | C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CC[C@@ ... | mono | 0 | norm_other | 0.012 | 30 | uM | 1 | Luc | H3A | liquid | in vitro | olf | rtp1s ric8b | dual-glo luciferase | rho | Keller, A., Zhuang, H., Chi, Q ... | https://doi.org/10.1038/nature ... | Fig_1A | |||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | (Z)-4-undecenal | 5362881 | QGNDNDFXCNBMKI-FPLPWBNLSA-N | CCCCCC/C=C\CCC=O | mono | 0 | norm_pair | 100 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor™-22f | il-6-halotag | The human odorant receptor OR1 ... | https://doi.org/10.1101/2020.1 ... | Fig_3 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 3-Methyl-2,4-nonanedione | 529481 | BGVBGAIWXAXBLP-UHFFFAOYSA-N | CCCCCC(=O)C(C)C(=O)C | sum of isomers | 0 | norm_rec | 30 | uM | 3 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor-22f | rho | The Broadly Tuned Odorant Rece ... | https://doi.org/10.1093/chemse ... | Fig_6 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | 3-Methyl-2,4-nonanedione | 529481 | BGVBGAIWXAXBLP-UHFFFAOYSA-N | CCCCCC(=O)C(C)C(=O)C | sum of isomers | 0 | norm_rec | 300 | uM | 3 | Luc | HEK | liquid | in vitro | olf | rtp1s gγ13 | glosensor-22f | rho | The Broadly Tuned Odorant Rece ... | https://doi.org/10.1093/chemse ... | Fig_S5 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | (e)-8-Cyclohexadecen-1-one | 5362739 | ZGEHHVDYDNXYMW-UPHRSURJSA-N | C1CCC/C=C\CCCCCCC(=O)CCC1 | mono | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | (5E)-3-methylcyclopentadec-5-en-1-one | 9834606 | NKMKFQCVDZVEJR-CSKARUKUSA-N | CC1C/C=C/CCCCCCCCCC(=O)C1 | mono | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | Ambrettolide | 5365703 | NVIPUOMWGQAOIT-RQOWECAXSA-N | C1CCCCOC(=O)CCCCC/C=C\CCC1 | mono | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | Galaxolide | 91497 | ONKNPOPIGWHAQC-UHFFFAOYSA-N | CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C | sum of isomers | 0 | norm_other | 100 | uM | 2 | Luc | H3A | liquid | in vitro | olf | rtp1 rtp2 reep1 | dualglo | rho | Diverse yet selective tuning o ... | https://doi.org/10.21203/rs.3. ... | Figure_S1 | ||||
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | L-Carvone | 439570 | 6485-40-1 | ULDHMXUKGWMISQ-SECBINFHSA-N | CC1=CC[C@H](CC1=O)C(=C)C | mono | 0 | norm_other | 0.948 | Fold | 300 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s cre luc2ppgl4.29 prl-cmv | dual-glo luciferase | rho | Ieki, Takashi, Yuki Yamanaka, ... | https://doi.org/10.1371/journa ... | Figure_1 | |
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | D-Carvone | 16724 | 2244-16-8 | ULDHMXUKGWMISQ-VIFPVBQESA-N | CC1=CC[C@@H](CC1=O)C(=C)C | mono | 0 | norm_other | 1.185 | Fold | 300 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s cre luc2ppgl4.29 prl-cmv | dual-glo luciferase | rho | Ieki, Takashi, Yuki Yamanaka, ... | https://doi.org/10.1371/journa ... | Figure_1 | |
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | cis-3-hexanol | 5281167 | 928-96-1 | UFLHIIWVXFIJGU-ARJAWSKDSA-N | CC/C=C\CCO | mono | 0 | norm_other | 1.138 | Fold | 1000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s cre luc2ppgl4.29 prl-cmv | dual-glo luciferase | rho | Ieki, Takashi, Yuki Yamanaka, ... | https://doi.org/10.1371/journa ... | Figure_1 | |
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | anis aldehyde | 31244 | 123-11-5 | ZRSNZINYAWTAHE-UHFFFAOYSA-N | COC1=CC=C(C=C1)C=O | mono | 0 | norm_other | 3.095 | Fold | 3000 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s cre luc2ppgl4.29 prl-cmv | dual-glo luciferase | rho | Ieki, Takashi, Yuki Yamanaka, ... | https://doi.org/10.1371/journa ... | Figure_1 | |
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | methyl beta-naphthyl ketone | 7122 | 93-08-3 | XSAYZAUNJMRRIR-UHFFFAOYSA-N | CC(=O)C1=CC2=CC=CC=C2C=C1 | mono | 0 | norm_other | 2.094 | Fold | 100 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s cre luc2ppgl4.29 prl-cmv | dual-glo luciferase | rho | Ieki, Takashi, Yuki Yamanaka, ... | https://doi.org/10.1371/journa ... | Figure_1 | |
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | linalool | 6549 | 78-70-6 | CDOSHBSSFJOMGT-UHFFFAOYSA-N | CC(=CCCC(C)(C=C)O)C | sum of isomers | 0 | norm_other | 0.878 | Fold | 300 | uM | 2 | Luc | HEK | liquid | in vitro | olf | rtp1s cre luc2ppgl4.29 prl-cmv | dual-glo luciferase | rho | Ieki, Takashi, Yuki Yamanaka, ... | https://doi.org/10.1371/journa ... | Figure_1 | |
homo sapiens | OR1A2 | Q9Y585 | MKKENQSFNLDFILL ... | cis-3-hexenol trans-2-hexenal | UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... | CC/C=C\CCO CCC/C=C/C=O | mixture | 0 | norm_other | 50 50 | uM | 2 | Luc | HEK | liquid | in vitro | rtp1s | dual-glo luciferase assay system (promega) | rho | Saito, Naoko, et al. "Involvem ... | https://doi.org/10.1371/journa ... | Figure_2 |