New Database Available - Released on 23/03/2024.
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157
Unique InChIKey
23
Unique Sequence
28
EC50 Parameter
15
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR1A2 Q9Y585 100 homo sapiens MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens A108G MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens K109N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens T154A MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens A108G_K109N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens G256C_W293C MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens A108G_V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_T154A MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens K109N_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_V205I_T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_V205I_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_T254V_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.382 homo sapiens A108G_K109N_V205I_T254V_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
Experiments Pair Aggregation
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Reference Position
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... (Z)-4-undecenal 5362881 QGNDNDFXCNBMKI-FPLPWBNLSA-N CCCCCC/C=C\CCC=O mono 0 norm_pair 100 uM 2 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor™-22f il-6-halotag The human odorant receptor OR1 ... https://doi.org/10.1101/2020.1 ... Fig_3
homo sapiens OR1A2 Q9Y585 A108G_K109N_T154A_S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 114 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 A108G_K109N_T154A MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 90 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 A108G_K109N_S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 138 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 A108G_T154A_S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 97 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 K109N_T154A_S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 116 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 T154A MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_S1
homo sapiens OR1A2 Q9Y585 A108G_V205I MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_V205I MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_T254V MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_T254V MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I_T254V MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I_T254V MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I_V277T MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I_V277T MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_T254V_V277T MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_T254V_V277T MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I_T254V_V277T MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N_V205I_T254V_V277T MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
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