New Database Available - Released on 23/03/2024.
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159
Unique InChIKey
24
Unique Sequence
28
EC50 Parameter
18
Unique DOI
BLAST
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR1A2 Q9Y585 100 homo sapiens MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens A108G MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens K109N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens T154A MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.676 homo sapiens R260C MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens A108G_K109N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens G256C_W293C MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.353 homo sapiens A108G_V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_T154A MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens K109N_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_V205I MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 99.029 homo sapiens A108G_K109N_T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_T154A_S155N MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_V205I_T254V MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_V205I_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.706 homo sapiens A108G_K109N_T254V_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
OR1A2 Q9Y585 98.382 homo sapiens A108G_K109N_V205I_T254V_V277T MKKENQSFNLDFILL ... MKKENQSFNLDFILL ...
Experiments Pair Aggregation
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homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.237 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.891 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.014 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.42 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... (-)-geosmin 29746 JLPUXFOGCDVKGO-TUAOUCFPSA-N C[C@H]1CCC[C@@]2([C@@]1(CCCC2)O)C mono 0 norm_pair 60 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Geosmin, a Food- and Water-Det ... https://pubs.acs.org/doi/10.10 ... Figure1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... 1,1,6-Trimethyl-1,2-dihydronaphthalene 121677 RTUMCNDCAVLXEP-UHFFFAOYSA-N CC1=CC2=C(C=C1)C(CC=C2)(C)C mono 0 norm_pair 100 uM 1 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag Petrol Note in Riesling – 1, ... https://doi.org/10.1021/acs.ja ... Figure1
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf tar-tat system glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4B
homo sapiens OR1A2 Q9Y585 MKKENQSFNLDFILL ... N-hexanal 6184 66-25-1 JARKCYVAAOWBJS-UHFFFAOYSA-N CCCCCC=O mono 0 raw 500 uM 1 Luc Flp-In T-Rex-293 liquid in vitro olf glosensor (promega) lucy flag rho Enhancement of transcription e ... https://doi.org/10.1371/journa ... Figure4A
homo sapiens OR1A2 Q9Y585 A108G MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 122 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 A108G MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 K109N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 94 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 K109N MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 K109N MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 1 ec50 99.4 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 A108G_K109N MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 A108G_K109N MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 T154A_S155N MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 V205I MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 V205I MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 V205I MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 T254V MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 T254V MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 T254V MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 V277T MKKENQSFNLDFILL ... (S)-(-)-citronellol 7793 QMVPMAAFGQKVCJ-JTQLQIEISA-N C[C@@H](CCC=C(C)C)CCO mono 0 ec50 n.d n.d 300 uM 2 Ca2+ HeLa/Olf liquid in vitro olf gtpγs aciii cnga2 flipr rho Structural determinants of odo ... https://doi.org/10.1016/j.jsb. ... Table_2
homo sapiens OR1A2 Q9Y585 V277T MKKENQSFNLDFILL ... (R)-(-)-Carvone 439570 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 V277T MKKENQSFNLDFILL ... (S)-(+)-Carvone 16724 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_pair 2000 uM 3 Luc HEK liquid in vitro olf rtp1s gγ13 glosensor-22f rho C. Geithe, J. Protze, F. Kreuc ... https://doi.org/10.1007/s00018 ... Fig_S3E
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR1A2 Q9Y585 G256C_W293C MKKENQSFNLDFILL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
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