New Database Available - Released on 23/03/2024.
121
Unique InChIKey
6
Unique Sequence
62
EC50 Parameter
16
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR5AN1 A0A6D2VXZ9 100 pongo abelii MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 A0A2J8LCK1 67.208 pan troglodytes W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... MTWGGNITEITYFIL ...
OR5AN1 A0A6D2VXZ9 66.558 pongo abelii G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 100 homo sapiens MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 99.678 homo sapiens L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 99.357 homo sapiens C142Y_L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
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Species
Gene Name
UniProt ID
Mutation
Sequence
Molecule Name
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Value
Unit
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Type
Cell_line
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DOI
Reference Position
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... methyl benzoate 7150 93-58-3 QPJVMBTYPHYUOC-UHFFFAOYSA-N COC(=O)C1=CC=CC=C1 mono 0 norm_other -0.269 100 uM 1 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 2,4-DNT 8461 121-14-2 RMBFBMJGBANMMK-UHFFFAOYSA-N CC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-] mono 0 norm_other -0.162 100 uM 1 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 1-Propanol, 2-[1-(3,3-dimethylcyclohexyl)ethoxy]-2-methyl-, 1-propanoate 16063567 141773-73-1 LSTSBZKIQFOPHA-UHFFFAOYSA-N CCC(=O)OCC(C)(C)OC(C)C1CCCC(C1)(C)C sum of isomers 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cyclopentadecane 67525 SRONXYPFSAKOGH-UHFFFAOYSA-N C1CCCCCCCCCCCCCC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cyclopentadecanol 107327 FFVHXGZXDRXFLQ-UHFFFAOYSA-N C1CCCCCCCC(CCCCCC1)O mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cyclohexanone 7967 JHIVVAPYMSGYDF-UHFFFAOYSA-N C1CCC(=O)CC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cyclodecanone 73918 SXOZDDAFVJANJP-UHFFFAOYSA-N C1CCCCC(=O)CCCC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cycloundecanone 13420 UPOSSYJVWXLPTA-UHFFFAOYSA-N C1CCCCCC(=O)CCCC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 2-pentadecanone 61303 CJPNOLIZCWDHJK-UHFFFAOYSA-N CCCCCCCCCCCCCC(=O)C mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 8-pentadecanone 13162 PQYGSSYFJIJDFK-UHFFFAOYSA-N CCCCCCCC(=O)CCCCCCC mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... ethylene brassylate 61014 105-95-3 XRHCAGNSDHCHFJ-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCCC1 mono 0 norm_other 0.141 0 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... ethylene brassylate 61014 105-95-3 XRHCAGNSDHCHFJ-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCCC1 mono 0 norm_other 0.119 1 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... ethylene brassylate 61014 105-95-3 XRHCAGNSDHCHFJ-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCCC1 mono 0 norm_other 0.118 10 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... ethylene brassylate 61014 105-95-3 XRHCAGNSDHCHFJ-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCCC1 mono 0 norm_other 0.224 100 uM 3 Luc H3A liquid in vitro olf rtp1 rtp2 reep1 dualglo rho Human olfactory receptor respo ... https://doi.org/10.1038/sdata. ... DataCitation_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 1 ec50 16.7 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_3A
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 1 ec50 0.79 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_3A
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Muscone 7160826 ALHUZKCOMYUFRB-OAHLLOKOSA-N C[C@@H]1CCCCCCCCCCCCC(=O)C1 mono 1 ec50 13.3 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_3B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... D-Muscone 7160827 ALHUZKCOMYUFRB-HNNXBMFYSA-N C[C@H]1CCCCCCCCCCCCC(=O)C1 mono 1 ec50 11.3 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_3B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 1 norm_other 140 100 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_4A
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Abhexone 61199 IUFQZPBIRYFPFD-UHFFFAOYSA-N CCC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Allyl Phenyl acetate 15717 1746-13-0 ZCDYAMJXVAUTIM-UHFFFAOYSA-N C=CCOC(=O)CC1=CC=CC=C1 mono 0 norm_rec 100 uM 2 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag IL-6–HaloTag® enables live- ... https://doi.org/10.14440/jbm.2 ... Figure_5
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 2,3,5-Trimethylpyrazine 26808 14667-55-1 IAEGWXHKWJGQAZ-UHFFFAOYSA-N CC1=CN=C(C(=N1)C)C mono 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1A
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 2,4,5-trimethyl-4,5-dihydrothiazole 263626 4145-93-1 CIEKNJJOENYFQL-UHFFFAOYSA-N CC1C(SC(=N1)C)C sum of isomers 0 norm_rec 100 uM 3 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag An evolutionary conserved olfa ... https://doi.org/10.1096/fj.202 ... Figure_1B
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 3-mercapto-2-methylpentan-1-ol 6430888 HABNNYNSJFKZFE-UHFFFAOYSA-N CCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_S1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 2-methyl-3-sulfanylpropan-1-ol 529079 FCIVYWQHILCTLI-UHFFFAOYSA-N CC(CO)CS sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 2-Methyl-3-sulfanylheptan-1-ol 21997288 OCZSUTGSYBERRF-UHFFFAOYSA-N CCCCC(C(C)CO)S sum of isomers 0 norm_rec 300 uM 3 Luc NxG108CC15 liquid in vitro olf gγ13 rtp1s glosensor (promega) rho OR2M3: a highly specific and n ... https://doi.org/10.1093/chemse ... Figure_3E