New Database Available - Released on 23/03/2024.
121
Unique InChIKey
6
Unique Sequence
62
EC50 Parameter
16
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR5AN1 A0A6D2VXZ9 100 pongo abelii MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 A0A2J8LCK1 67.208 pan troglodytes W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... MTWGGNITEITYFIL ...
OR5AN1 A0A6D2VXZ9 66.558 pongo abelii G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 100 homo sapiens MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 99.678 homo sapiens L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 99.357 homo sapiens C142Y_L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
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Species
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UniProt ID
Mutation
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Molecule Name
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Cell_line
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DOI
Reference Position
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... celestolide 61585 IKTHMQYJOWTSJO-UHFFFAOYSA-N CC(=O)C1=C2CCC(C2=CC(=C1)C(C)(C)C)(C)C mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... cashmeran 92292 MIZGSAALSYARKU-UHFFFAOYSA-N CC1C(C2=C(C1(C)C)C(=O)CCC2)(C)C sum of isomers 1 norm_other 0.1 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... 1-Propanol, 2-[1-(3,3-dimethylcyclohexyl)ethoxy]-2-methyl-, 1-propanoate 16063567 141773-73-1 LSTSBZKIQFOPHA-UHFFFAOYSA-N CCC(=O)OCC(C)(C)OC(C)C1CCCC(C1)(C)C sum of isomers 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... cyclopentadecane 67525 SRONXYPFSAKOGH-UHFFFAOYSA-N C1CCCCCCCCCCCCCC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... cyclopentadecanol 107327 FFVHXGZXDRXFLQ-UHFFFAOYSA-N C1CCCCCCCC(CCCCCC1)O mono 1 norm_other 8 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... cyclohexanone 7967 JHIVVAPYMSGYDF-UHFFFAOYSA-N C1CCC(=O)CC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... cyclodecanone 73918 SXOZDDAFVJANJP-UHFFFAOYSA-N C1CCCCC(=O)CCCC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... cycloundecanone 13420 UPOSSYJVWXLPTA-UHFFFAOYSA-N C1CCCCCC(=O)CCCC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... 2-pentadecanone 61303 CJPNOLIZCWDHJK-UHFFFAOYSA-N CCCCCCCCCCCCCC(=O)C mono 1 norm_other 0.1 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pan troglodytes OR5AN1 A0A2J8LCK1 W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... 8-pentadecanone 13162 PQYGSSYFJIJDFK-UHFFFAOYSA-N CCCCCCCC(=O)CCCCCCC mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 1 ec50 5.5 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_1C
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... (+/-)-Muscone 10947 541-91-3 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 1 norm_other 13 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... 3-methylcyclopentadec-5-en-1-one 54116156 NKMKFQCVDZVEJR-UHFFFAOYSA-N CC1CC=CCCCCCCCCCC(=O)C1 sum of isomers 1 norm_other 15 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... cyclopentadecanone 10409 OSOIQJGOYGSIMF-UHFFFAOYSA-N C1CCCCCCCC(=O)CCCCCC1 mono 1 norm_other 12 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... 5-Cyclohexadecen-1-one 162268 ABRIMXGLNHCLIP-UHFFFAOYSA-N C1CCCCCC(=O)CCCC=CCCCC1 mono 1 norm_other 18 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... (8E)-cyclohexadec-8-en-1-one 6365152 ZGEHHVDYDNXYMW-OWOJBTEDSA-N C1CCC/C=C/CCCCCCC(=O)CCC1 mono 1 norm_other 15 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... (E)-3-Methylcyclotetradeca-5-ene-1-one 66823518 259854-70-1 ZFGBKXBPHOUSJX-VQHVLOKHSA-N CC1C/C=C/CCCCCCCCC(=O)C1 mono 1 norm_other 7 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... 3-methylcyclotetradecan-1-one 11253089 VPQWBNWSLZYYFH-UHFFFAOYSA-N CC1CCCCCCCCCCCC(=O)C1 sum of isomers 1 norm_other 2 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... ethylene brassylate 61014 XRHCAGNSDHCHFJ-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCCC1 mono 1 norm_other 3 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... ambrettolide 5365703 NVIPUOMWGQAOIT-RQOWECAXSA-N C1CCCCOC(=O)CCCCC/C=C\CCC1 mono 1 norm_other 5 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... exaltolide 235414 FKUPPRZPSYCDRS-UHFFFAOYSA-N C1CCCCCCCOC(=O)CCCCCC1 mono 1 norm_other 1 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... habanolide 12410118 KHLFMZDGADSQGR-ACCUITESSA-N C1CCCCCCOC(=O)/C=C/CCCCC1 mono 1 norm_other 1 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... musk xylol 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... musk ketone 6669 WXCMHFPAUCOJIG-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 1 norm_other 4 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... galaxolide 91497 ONKNPOPIGWHAQC-UHFFFAOYSA-N CC1COCC2=CC3=C(C=C12)C(C(C3(C)C)C)(C)C sum of isomers 1 norm_other 0.4 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... tonalide 89440 DNRJTBAOUJJKDY-UHFFFAOYSA-N CC1CC(C2=C(C1(C)C)C=C(C(=C2)C(=O)C)C)(C) ... sum of isomers 1 norm_other 0.1 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... celestolide 61585 IKTHMQYJOWTSJO-UHFFFAOYSA-N CC(=O)C1=C2CCC(C2=CC(=C1)C(C)(C)C)(C)C mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... cashmeran 92292 MIZGSAALSYARKU-UHFFFAOYSA-N CC1C(C2=C(C1(C)C)C(=O)CCC2)(C)C sum of isomers 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... 1-Propanol, 2-[1-(3,3-dimethylcyclohexyl)ethoxy]-2-methyl-, 1-propanoate 16063567 141773-73-1 LSTSBZKIQFOPHA-UHFFFAOYSA-N CCC(=O)OCC(C)(C)OC(C)C1CCCC(C1)(C)C sum of isomers 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B
pongo abelii OR5AN1 A0A6D2VXZ9 G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... cyclopentadecane 67525 SRONXYPFSAKOGH-UHFFFAOYSA-N C1CCCCCCCCCCCCCC1 mono 0 norm_other 0 10 uM 3 Luc HEK liquid in vitro rtp1s-pme18s dual-glo luciferase assay system flag Ligand specificity and evoluti ... https://doi.org/10.1523/JNEURO ... Figure_2B