New Database Available - Released on 23/03/2024.
121
Unique InChIKey
6
Unique Sequence
62
EC50 Parameter
16
Unique DOI
Gene Name
UniProt ID
% Seq Identity
Species
Mutation
Sequence
Ref. Sequence
OR5AN1 A0A6D2VXZ9 100 pongo abelii MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 A0A2J8LCK1 67.208 pan troglodytes W3G_G4E_G5R_I7S_E9R_Y12K_D20E_ ... MTGERNSTRITKFIL ... MTWGGNITEITYFIL ...
OR5AN1 A0A6D2VXZ9 66.558 pongo abelii G4E_G5R_I7S_E9R_Y12K_D20E_R23K ... MTGERNSTRITKFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 100 homo sapiens MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 99.678 homo sapiens L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
OR5AN1 Q8NGI8 99.357 homo sapiens C142Y_L289F MTGGGNITEITYFIL ... MTGGGNITEITYFIL ...
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Species
Gene Name
UniProt ID
Mutation
Sequence
Molecule Name
CID
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Value
Unit
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Type
Cell_line
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Reference
DOI
Reference Position
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Muscone 10947 ALHUZKCOMYUFRB-UHFFFAOYSA-N CC1CCCCCCCCCCCCC(=O)C1 sum of isomers 1 ec50 39.811 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Ethylene brassylate 61014 XRHCAGNSDHCHFJ-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCCC1 mono 1 ec50 501.187 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Cosmone 54543965 ZFGBKXBPHOUSJX-UHFFFAOYSA-N CC1CC=CCCCCCCCCC(=O)C1 sum of isomers 1 ec50 2.512 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Musk MC4 41270 GJJSUPSPZIZYPM-UHFFFAOYSA-N C1CCCCCC(=O)OCCOC(=O)CCCC1 mono 1 ec50 12.589 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Muscenone 54116156 NKMKFQCVDZVEJR-UHFFFAOYSA-N CC1CC=CCCCCCCCCCC(=O)C1 sum of isomers 1 ec50 1.585 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Thibetolide 235414 FKUPPRZPSYCDRS-UHFFFAOYSA-N C1CCCCCCCOC(=O)CCCCCC1 mono 1 ec50 19.953 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Velvione 5362736 ABRIMXGLNHCLIP-VURMDHGXSA-N C1CCCCCC(=O)CCC/C=C\CCCC1 mono 1 ec50 5.012 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Cyclopentadecanone 10409 OSOIQJGOYGSIMF-UHFFFAOYSA-N C1CCCCCCCC(=O)CCCCCC1 mono 1 ec50 7.943 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Nirvanolide 11064468 NUSRNVWNTPMBJA-VURMDHGXSA-N CC1CCOC(=O)CCCCCCC/C=C\C1 mono 1 ec50 158.489 uM 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Helvetolide 16063567 LSTSBZKIQFOPHA-UHFFFAOYSA-N CCC(=O)OCC(C)(C)OC(C)C1CCCC(C1)(C)C sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Serenolide 12022011 BZLYOWSSNHNYKW-UHFFFAOYSA-N CC(C1CCCC(C1)(C)C)OC(C)(C)COC(=O)C2CC2 sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... Sylkolide 11277198 ZYIJXTQXQNXPSH-FMIVXFBMSA-N CC(C)/C=C(\C)/C(C)OC(C)(C)COC(=O)C1CC1 mono 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... 1-(3,3-dimethylcyclohexyl)ethyl acetate 91339 YWVSYRJWCROMKO-UHFFFAOYSA-N CC(C1CCCC(C1)(C)C)OC(=O)C sum of isomers 0 ec50 n.d n.d 3 Luc HEK liquid in vitro hrtp1s/hrtp2 Functional characterization of ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... musk xylene 62329 XMWRWTSZNLOZFN-UHFFFAOYSA-N CC1=C(C(=C(C(=C1[N+](=O)[O-])C(C)(C)C)[N ... mono 1 ec50 4.2 uM 17 Luc HEK liquid in vitro hrtp1s/hrtp2 Human olfactory receptors deor ... https://doi.org/10.1093/chemse ... Table_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone 439570 6485-40-1 ULDHMXUKGWMISQ-SECBINFHSA-N CC1=CC[C@H](CC1=O)C(=C)C mono 0 norm_other 1.227 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... D-Carvone 16724 2244-16-8 ULDHMXUKGWMISQ-VIFPVBQESA-N CC1=CC[C@@H](CC1=O)C(=C)C mono 0 norm_other 1.659 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cis-3-hexanol 5281167 928-96-1 UFLHIIWVXFIJGU-ARJAWSKDSA-N CC/C=C\CCO mono 0 norm_other 1.047 Fold 1000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... anis aldehyde 31244 123-11-5 ZRSNZINYAWTAHE-UHFFFAOYSA-N COC1=CC=C(C=C1)C=O mono 0 norm_other 3.663 Fold 3000 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... methyl beta-naphthyl ketone 7122 93-08-3 XSAYZAUNJMRRIR-UHFFFAOYSA-N CC(=O)C1=CC2=CC=CC=C2C=C1 mono 0 norm_other 1.984 Fold 100 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... linalool 6549 78-70-6 CDOSHBSSFJOMGT-UHFFFAOYSA-N CC(=CCCC(C)(C=C)O)C sum of isomers 0 norm_other 0.962 Fold 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_1
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... cis-3-hexenol trans-2-hexenal UFLHIIWVXFIJGU-ARJAWSKDSA-N MB ... CC/C=C\CCO CCC/C=C/C=O mixture 0 norm_other 50 50 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... MCMP XSAYZAUNJMRRIR-UHFFFAOYSA-N UL ... CC(=O)C1=CC2=CC=CC=C2C=C1 CC1=CC[C@H](CC ... mixture 0 norm_other 75 75 75 75 uM 2 Luc HEK liquid in vitro rtp1s dual-glo luciferase assay system (promega) rho Saito, Naoko, et al. "Involvem ... https://doi.org/10.1371/journa ... Figure_4
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 2.326 Fold 100 300 100 100 100 300 uM 2 Luc HEK liquid in vitro olf rtp1s cre luc2ppgl4.29 prl-cmv dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.281 Fold 100 300 100 100 100 300 uM 2 Luc HEPG2 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 1.09 Fold 100 300 100 100 100 300 uM 2 Luc HUH7 liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 MTGGGNITEITYFIL ... L-Carvone d-Carvone cis-3-hexenol anis aldehyde methyl-beta-naphthyl ketone linalool ULDHMXUKGWMISQ-SECBINFHSA-N UL ... CC1=CC[C@H](CC1=O)C(=C)C CC1=CC[C@@H](CC ... mixture 0 norm_other 0.625 Fold 100 300 100 100 100 300 uM 2 Luc LNCAP liquid in vitro olf dual-glo luciferase rho Ieki, Takashi, Yuki Yamanaka, ... https://doi.org/10.1371/journa ... Figure_2
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... 3-Mercaptohexyl acetate 518810 JUCARGIKESIVLB-UHFFFAOYSA-N CCCC(CCOC(=O)C)S sum of isomers 0 norm_rec 100 uM 2 Luc HEK liquid in vitro olf gγ13 rtp1s glosensor (promega) il-6-halotag The key food odorant receptive ... https://doi.org/10.1016/j.food ... Figure_S3
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... Furaneol 19309 INAXVXBDKKUCGI-UHFFFAOYSA-N CC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... Sotolone 62835 UNYNVICDCJHOPO-UHFFFAOYSA-N CC1C(=C(C(=O)O1)O)C sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1
homo sapiens OR5AN1 Q8NGI8 L289F MTGGGNITEITYFIL ... homofuraneol 33931 GWCRPYGYVRXVLI-UHFFFAOYSA-N CCC1C(=O)C(=C(O1)C)O sum of isomers 0 norm_rec 1000 uM 2 Luc HEK liquid in vitro olf rtp1s glosensor (promega) il-6-halotag Key food furanones furaneol an ... https://doi.org/10.1021/acs.ja ... Figure_1